Targeting a new regulator of erythropoiesis to alleviate anemia

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作者
Robert F Paulson
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[1] Robert F. Paulson is at the Center for Molecular Immunology and Infectious Disease,Department of Veterinary and Biomedical Sciences
[2] The Pennsylvania State University,undefined
[3] University Park,undefined
[4] Pennsylvania,undefined
[5] USA.,undefined
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Nature Medicine | 2014年 / 20卷
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摘要
Anemia is a debilitating condition that can be complicated by ineffective erythropoiesis. Two new studies identify GDF11 as a regulator of erythropoiesis and show that its inhibition in mouse models of anemia with ineffective erythropoiesis restores normal erythropoietic differentiation and alleviates anemia (pages 398–407 and 408–414).
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页码:334 / 335
页数:1
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