Synthesis of methyl esters of 5-aroyl-6-aryl-2-oxo-1,2,3,6-tetra-hydropyrimidine-4-carboxylic acids

被引：0
|
作者：
V. L. Gein
I. V. Krylova
E. P. Tsypliakova
A. R. Gaifullina
L. I. Varkentin
M. I. Vakhrin
机构：
[1] Perm State Pharmaceutical Academy,
[2] Perm State Medicinal Academy,undefined
来源：
Chemistry of Heterocyclic Compounds | 2009年 / 45卷
关键词：
hydrazine hydrate; 8-hydroxy-4,5-diphenyl-3,4-dihydropyrimido[4,5-; ]-pyridazin-2(1H)-one; substituted benzaldehydes; methyl esters of 5-aroyl-6-aryl-2-oxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acids; urea; esters of aroylpyruvic acids;
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学科分类号：
摘要：
Methyl esters of 5-aroyl-6-aryl-2-oxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acids were synthesized from three component mixtures of methyl esters of aroylpyruvic acids, urea, and substituted benzaldehydes. 8-Hydroxy-4,5-diphenyl-3,4-dihydropyrimido[4,5-d]pyridazin-2(1H)-one was synthesized by the reaction of 5-benzoyl-2-oxo-6-phenyl-1,2,3,6-tetrahydropyrimidin-4-carboxylate with hydrazine hydrate.
引用
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页码：829 / 832
页数：3
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