The role of dendritic cells in the pharynx

被引:0
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作者
Jan Plzák
Zuzana Holíková
Karel Smetana
Frank Riedel
Jan Betka
机构
[1] Department of Otorhinolaryngology and Head and Neck Surgery,
[2] First Faculty of Medicine,undefined
[3] Charles University,undefined
[4] Postgraduate Medical School,undefined
[5] Faculty Hospital Motol,undefined
[6] V Úvalu 84,undefined
[7] 150 06 Prague 5,undefined
[8] Czech Republic,undefined
[9] Institute of Anatomy,undefined
[10] First Faculty of Medicine,undefined
[11] Charles University,undefined
[12] Prague,undefined
[13] Czech Republic,undefined
[14] Department of Dermatovenerology,undefined
[15] Second Faculty of Medicine,undefined
[16] Charles University,undefined
[17] Prague,undefined
[18] Czech Republic,undefined
[19] Center of Cell Therapy and Tissue Repair,undefined
[20] Second Faculty of Medicine,undefined
[21] Charles University,undefined
[22] Prague,undefined
[23] Czech Republic,undefined
[24] Department of Otolaryngology and Head and Neck Surgery,undefined
[25] University Hospital of Mannheim,undefined
[26] Mannheim,undefined
[27] Germany,undefined
关键词
Antigen-presenting cells Dendritic cells Tonsil Immune response;
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学科分类号
摘要
The tonsils are organized as lymphoepithelial structures that play an important role in protecting both the upper respiratory and alimentary tract regions against incoming antigens. This function requires dendritic cells, professional antigen-presenting cells that act as peripheral sentinels, specializing in the uptake, processing and presentation of antigenic material. This article gives a brief review on dendritic cells with regard to their origin, life cycle and functions in the pharyngeal mucosa. The regulation of immune responses in tonsils by dendritic cells is discussed. Their importance in some disease states is also mentioned.
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页码:266 / 272
页数:6
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