A panel of CSF proteins separates genetic frontotemporal dementia from presymptomatic mutation carriers: a GENFI study

被引：0

作者：

Sofia Bergström

Linn Öijerstedt

Julia Remnestål

Jennie Olofsson

Abbe Ullgren

Harro Seelaar

John C. van Swieten

Matthis Synofzik

Raquel Sanchez-Valle

Fermin Moreno

Elizabeth Finger

Mario Masellis

Carmela Tartaglia

Rik Vandenberghe

Robert Laforce

Daniela Galimberti

Barbara Borroni

Chris R. Butler

Alexander Gerhard

Simon Ducharme

Jonathan D. Rohrer

Anna Månberg

Caroline Graff

Peter Nilsson

机构：

[1] KTH Royal Institute of Technology,Division of Affinity Proteomics, Department of Protein Science

[2] SciLifeLab,Department of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, Unit of Hereditary Dementias

[3] Swedish FTD Initiative,Unit for Hereditary Dementias, Theme Aging

[4] Theme Aging,Department of Neurology

[5] Karolinska University Hospital,Department of Neurodegenerative Diseases

[6] Karolinska University Hospital,Alzheimer’s disease and Other Cognitive Disorders Unit

[7] Erasmus Medical Centre,Cognitive Disorders Unit, Department of Neurology

[8] Hertie-Institute for Clinical Brain Research and Center of Neurology,Department of Clinical Neurological Sciences

[9] University of Tübingen,Sunnybrook Health Sciences Centre, Sunnybrook Research Institute

[10] Center for Neurodegenerative Diseases (DZNE),Tanz Centre for Research in Neurodegenerative Diseases

[11] Neurology Service,Laboratory for Cognitive Neurology, Department of Neurosciences

[12] Hospital Clínic,Neurology Service

[13] Institut d’Investigacións Biomèdiques August Pi I Sunyer,Clinique Interdisciplinaire de Mémoire, Département des Sciences Neurologiques

[14] University of Barcelona,Centre for Neurodegenerative Disorders, Department of Clinical and Experimental Sciences

[15] Donostia University Hospital,Nuffield Department of Clinical Neurosciences, Medical Sciences Division

[16] Neuroscience Area,Department of Brain Sciences

[17] Biodonostia Health Research Institute,Division of Neuroscience and Experimental Psychology

[18] University of Western Ontario,Departments of Geriatric Medicine and Nuclear Medicine

[19] University of Toronto,Department of Psychiatry

[20] University of Toronto,McConnell Brain Imaging Centre

[21] KU Leuven,Department of Neurodegenerative Disease

[22] University Hospitals Leuven,undefined

[23] Leuven Brain Institute,undefined

[24] KU Leuven,undefined

[25] CHU de Québec,undefined

[26] and Faculté de Médecine,undefined

[27] Université Laval,undefined

[28] Fondazione IRCCS Ospedale Policlinico,undefined

[29] University of Milan,undefined

[30] Centro Dino Ferrari,undefined

[31] University of Brescia,undefined

[32] University of Oxford,undefined

[33] Imperial College London,undefined

[34] Wolfson Molecular Imaging Centre,undefined

[35] University of Manchester,undefined

[36] University of Duisburg- Essen,undefined

[37] Douglas Mental Health University Institute,undefined

[38] McGill University,undefined

[39] Montreal Neurological Institute,undefined

[40] McGill University,undefined

[41] Dementia Research Centre,undefined

[42] UCL Institute of Neurology,undefined

来源：

Molecular Neurodegeneration | / 16卷

关键词：

Cerebrospinal fluid; Neurofilament medium polypeptide (NEFM); Neuronal pentraxin 2 (NPTX2); Neurosecretory protein VGF (VGF); Aquaporin 4 (AQP4); LASSO; Random forest; Suspension bead array;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

引用

共 37 条

[1] A panel of CSF proteins separates genetic frontotemporal dementia from presymptomatic mutation carriers: a GENFI study
Bergstrom, Sofia
Oijerstedt, Linn
Remnestal, Julia
Olofsson, Jennie
Ullgren, Abbe
Seelaar, Harro
van Swieten, John C.
Synofzik, Matthis
Sanchez-Valle, Raquel
Moreno, Fermin
Finger, Elizabeth
Masellis, Mario
Tartaglia, Carmela
Vandenberghe, Rik
Laforce, Robert
Galimberti, Daniela
Borroni, Barbara
Butler, Chris R.
Gerhard, Alexander
Ducharme, Simon
Rohrer, Jonathan D.
Manberg, Anna
Graff, Caroline
Nilsson, Peter
[J]. MOLECULAR NEURODEGENERATION, 2021, 16 (01)
[2] Elevated CSF and plasma complement proteins in genetic frontotemporal dementia: results from the GENFI study
Emma L. van der Ende
Carolin Heller
Aitana Sogorb-Esteve
Imogen J. Swift
David McFall
Georgia Peakman
Arabella Bouzigues
Jackie M. Poos
Lize C. Jiskoot
Jessica L. Panman
Janne M. Papma
Lieke H. Meeter
Elise G. P. Dopper
Martina Bocchetta
Emily Todd
David Cash
Caroline Graff
Matthis Synofzik
Fermin Moreno
Elizabeth Finger
Raquel Sanchez-Valle
Rik Vandenberghe
Robert Laforce
Mario Masellis
Maria Carmela Tartaglia
James B. Rowe
Chris Butler
Simon Ducharme
Alexander Gerhard
Adrian Danek
Johannes Levin
Yolande A. L. Pijnenburg
Markus Otto
Barbara Borroni
Fabrizio Tagliavini
Alexandre de Mendonça
Isabel Santana
Daniela Galimberti
Sandro Sorbi
Henrik Zetterberg
Eric Huang
John C. van Swieten
Jonathan D. Rohrer
Harro Seelaar
[J]. Journal of Neuroinflammation, 19
[3] Cerebral perfusion changes in presymptomatic genetic frontotemporal dementia: a GENFI study
Mutsaerts, Henri J. M. M.
Mirza, Saira S.
Petr, Jan
Thomas, David L.
Cash, David M.
Bocchetta, Martina
de Vita, Enrico
Metcalfe, Arron W. S.
Shirzadi, Zahra
Robertson, Andrew D.
Tartaglia, Maria Carmela
Mitchell, Sara B.
Black, Sandra E.
Freedman, Morris
Tang-Wai, David
Keren, Ron
Rogaeva, Ekaterina
van Swieten, John
Laforce, Robert, Jr.
Tagliavini, Fabrizio
Borroni, Barbara
Galimberti, Daniela
Rowe, James B.
Graff, Caroline
Frisoni, Giovanni B.
Finger, Elizabeth
Sorbi, Sandro
de Mendonca, Alexandre
Rohrer, Jonathan D.
MacIntosh, Bradley J.
Masellis, Mario
[J]. BRAIN, 2019, 142 : 1108 - 1120
[4] Elevated CSF and plasma complement proteins in genetic frontotemporal dementia: results from the GENFI study
van der Ende, Emma L.
Heller, Carolin
Sogorb-Esteve, Aitana
Swift, Imogen J.
McFall, David
Peakman, Georgia
Bouzigues, Arabella
Poos, Jackie M.
Jiskoot, Lize C.
Panman, Jessica L.
Papma, Janne M.
Meeter, Lieke H.
Dopper, Elise G. P.
Bocchetta, Martina
Todd, Emily
Cash, David
Graff, Caroline
Synofzik, Matthis
Moreno, Fermin
Finger, Elizabeth
Sanchez-Valle, Raquel
Vandenberghe, Rik
Laforce, Robert, Jr.
Masellis, Mario
Tartaglia, Maria Carmela
Rowe, James B.
Butler, Chris
Ducharme, Simon
Gerhard, Alexander
Danek, Adrian
Levin, Johannes
Pijnenburg, Yolande A. L.
Otto, Markus
Borroni, Barbara
Tagliavini, Fabrizio
de Mendonca, Alexandre
Santana, Isabel
Galimberti, Daniela
Sorbi, Sandro
Zetterberg, Henrik
Huang, Eric
van Swieten, John C.
Rohrer, Jonathan D.
Seelaar, Harro
[J]. JOURNAL OF NEUROINFLAMMATION, 2022, 19 (01)
[5] Inflammatory plasma profile in genetic symptomatic and presymptomatic Frontotemporal Dementia - A GENFI study
Fenoglio, Chiara
Serpente, Maria
Arcaro, Marina
Carandini, Tiziana
Sacchi, Luca
Pintus, Manuela
Rotondo, Emanuela
Borracci, Vittoria
Ghezzi, Laura
Bouzigues, Arabella
Russell, Lucy L.
Foster, Phoebe H.
Ferry-Bolder, Eve
van Swieten, John C.
Jiskoot, Lize C.
Seelaar, Harro
Valle, Raquel Sanchez
Laforce, Robert
Graff, Caroline
Vandenberghe, Rik
de Mendonca, Alexandre
Tiraboschi, Pietro
Santana, Isabel
Gerhard, Alexander
Levin, Johannes
Sorbi, Sandro
Otto, Markus
Pasquier, Florence
Ducharme, Simon
Butler, Chris R.
Le Ber, Isabelle
Finger, Elizabeth
Tartaglia, Maria Carmela
Masellis, Mario
Rowe, James B.
Synofzik, Matthis
Moreno, Fermin
Borroni, Barbara
Rohrer, Jonathan D.
Arighi, Andrea
Galimberti, Daniela
[J]. BRAIN BEHAVIOR AND IMMUNITY, 2024, 122 : 231 - 240
[6] Presymptomatic cerebral perfusion biomarker changes in genetic frontotemporal dementia: results from the GENetic Frontotemporal dementia Initiative (GENFI)
Mutsaerts, H.
Mirza, S. S.
Rohrer, J.
Thomas, D.
Cash, D.
De Vita, E.
Dick, K.
Ourselin, S.
van Swieten, J.
Galimberti, D.
Rowe, J. B.
Graff, C.
Tagliavini, F.
Laforce, R., Jr.
Finger, E.
Mendonca, A.
Knight, J.
MacIntosh, B.
Masellis, M.
[J]. JOURNAL OF NEUROCHEMISTRY, 2016, 138 : 404 - 404
[7] Longitudinal cerebral perfusion in presymptomatic genetic frontotemporal dementia: GENFI results
Pasternak, Maurice
Mirza, Saira S.
Luciw, Nicholas
Mutsaerts, Henri J. M. M.
Petr, Jan
Thomas, David
Cash, David
Bocchetta, Martina
Tartaglia, Maria Carmela
Mitchell, Sara B.
Black, Sandra E.
Freedman, Morris
Tang-Wai, David
Rogaeva, Ekaterina
Russell, Lucy L.
Bouzigues, Arabella
van Swieten, John C.
Jiskoot, Lize C.
Seelaar, Harro
Laforce, Robert, Jr.
Tiraboschi, Pietro
Borroni, Barbara
Galimberti, Daniela
Rowe, James B.
Graff, Caroline
Finger, Elizabeth
Sorbi, Sandro
de Mendonca, Alexandre
Butler, Chris
Gerhard, Alex
Sanchez-Valle, Raquel
Moreno, Fermin
Synofzik, Matthis
Vandenberghe, Rik
Ducharme, Simon
Levin, Johannes
Otto, Markus
Santana, Isabel
Strafella, Antonio P.
MacIntosh, Bradley J.
Rohrer, Jonathan D.
Masellis, Mario
[J]. ALZHEIMERS & DEMENTIA, 2024, 20 (05) : 3525 - 3542
[8] Presymptomatic cognitive and neuroanatomical changes in genetic frontotemporal dementia in the Genetic Frontotemporal dementia Initiative (GENFI) study: a cross-sectional analysis
Rohrer, Jonathan D.
Nicholas, Jennifer M.
Cash, David M.
van Swieten, John
Dopper, Elise
Jiskoot, Lize
van Minkelen, Rick
Rombouts, Serge A.
Cardoso, M. Jorge
Clegg, Shona
Espak, Miklos
Mead, Simon
Thomas, David L.
De Vita, Enrico
Masellis, Mario
Black, Sandra E.
Freedman, Morris
Keren, Ron
MacIntosh, Bradley J.
Rogaeva, Ekaterina
Tang-Wai, David
Tartaglia, Maria Carmelo
Laforce, Robert, Jr.
Tagliavini, Fabrizio
Tiraboschi, Pietro
Redaelli, Veronica
Prioni, Sara
Grisoli, Marina
Borroni, Barbara
Padovani, Alessandro
Galimberti, Daniela
Scarpini, Elio
Arighi, Andrea
Fumagalli, Giorgio
Rowe, James B.
Coyle-Gilchrist, Ian
Graff, Caroline
Fallstrom, Marie
Jelic, Vesna
Stahlbom, Anne Kinhult
Andersson, Christin
Thonberg, Hakan
Lilius, Lena
Frisoni, Giovanni B.
Pievani, Michela
Bocchetta, Martina
Benussi, Luisa
Ghidoni, Roberta
Finger, Elizabeth
Sorbi, Sandro
[J]. LANCET NEUROLOGY, 2015, 14 (03): : 253 - 262
[9] Impairment of episodic memory in genetic frontotemporal dementia: A GENFI study
Poos, Jackie M.
Russell, Lucy L.
Peakman, Georgia
Bocchetta, Martina
Greaves, Caroline V.
Jiskoot, Lize C.
van der Ende, Emma L.
Seelaar, Harro
Papma, Janne M.
van den Berg, Esther
Pijnenburg, Yolande A. L.
Borroni, Barbara
Sanchez-Valle, Raquel
Moreno, Fermin
Laforce, Robert
Graff, Caroline
Synofzik, Matthias
Galimberti, Daniela
Rowe, James B.
Masellis, Mario
Tartaglia, Carmela
Finger, Elizabeth
Vandenberghe, Rik
de Medonca, Alexandre
Tagliavini, Fabrizio
Butler, Chris R.
Santana, Isabel
Le Ber, Isabelle
Gerhard, Alex
Ducharme, Simon
Levin, Johannes
Danek, Adrian
Otto, Markus
Sorbi, Sandro
Pasquier, Florence
van Swieten, John C.
Rohrer, Jonathan D.
[J]. ALZHEIMER'S & DEMENTIA: DIAGNOSIS, ASSESSMENT & DISEASE MONITORING, 2021, 13 (01)
[10] Impaired glymphatic system in genetic frontotemporal dementia: a GENFI study
Premi, Enrico
Diano, Matteo
Mattioli, Irene
Altomare, Daniele
Cantoni, Valentina
Bocchetta, Martina
Gasparotti, Roberto
Buratti, Emanuele
Pengo, Marta
Bouzigues, Arabella
Russell, Lucy L.
Foster, Phoebe H.
Ferry-Bolder, Eve
Heller, Carolin
van Swieten, John C.
Jiskoot, Lize C.
Seelaar, Harro
Moreno, Fermin
Sanchez-Valle, Raquel
Galimberti, Daniela
Laforce, Robert
Graff, Caroline
Masellis, Mario
Tartaglia, Maria Carmela
Rowe, James B.
Finger, Elizabeth
Vandenberghe, Rik
de Mendonca, Alexandre
Butler, Chris R.
Gerhard, Alexander
Ducharme, Simon
Le Ber, Isabelle
Tiraboschi, Pietro
Santana, Isabel
Pasquier, Florence
Synofzik, Matthis
Levin, Johannes
Otto, Markus
Sorbi, Sandro
Rohrer, Jonathan D.
Borroni, Barbara
[J]. BRAIN COMMUNICATIONS, 2024, 6 (04)

← 1 2 3 4 →