Prophylactic surgery prevents endometrial and ovarian cancer in Lynch syndrome

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Henry T Lynch
Murray Joseph Casey
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[1] Omaha,HT Lynch is Professor of Medicine and Chair of the Department of Preventive Medicine and Public Health and MJ Casey is Professor of Obstetrics and Gynecology and Director of Gynecologic Oncology at Creighton University School of Medicine
[2] NE,undefined
[3] USA.,undefined
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Women who carry a germline mismatch-repair mutation causal to Lynch syndrome have increased risks of developing endometrial carcinoma and ovarian cancer, as well as colorectal carcinoma. This Viewpoint outlines the rationale for the use of lifesaving prophylactic gynecologic surgery in these women following childbearing, with testing and surveillance unless and until such surgery is performed.
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页码:672 / 673
页数:1
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