Synthesis and characterization in monkey of [11C]SP203 as a radioligand for imaging brain metabotropic glutamate 5 receptors

被引：0
|
作者：
Fabrice G. Siméon
Jeih-San Liow
Yi Zhang
Jinsoo Hong
Robert L. Gladding
Sami S. Zoghbi
Robert B. Innis
Victor W. Pike
机构：
[1] National Institutes of Health,Molecular Imaging Branch, National Institute of Mental Health
[2] National Institutes of Health,Molecular Imaging Branch, National Institute of Mental Health
来源：
European Journal of Nuclear Medicine and Molecular Imaging | 2012年 / 39卷
关键词：
Radioligand; PET; mGluR5; Carbon-11; SP203;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：1949 / 1958
页数：9
相关论文
共 50 条
  • [1] Synthesis and characterization in monkey of [11C]SP203 as a radioligand for imaging brain metabotropic glutamate 5 receptors
    Simeon, Fabrice G.
    Liow, Jeih-San
    Zhang, Yi
    Hong, Jinsoo
    Gladding, Robert L.
    Zoghbi, Sami S.
    Innis, Robert B.
    Pike, Victor W.
    [J]. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2012, 39 (12) : 1949 - 1958
  • [2] Comparison of two PET radioligands, [11C]FPEB and [11C]SP203, for quantification of metabotropic glutamate receptor 5 in human brain
    Lohith, Talakad G.
    Tsujikawa, Tetsuya
    Simeon, Fabrice G.
    Veronese, Mattia
    Zoghbi, Sami S.
    Lyoo, Chul Hyoung
    Kimura, Yasuyuki
    Morse, Cheryl L.
    Pike, Victor W.
    Fujita, Masahiro
    Innis, Robert B.
    [J]. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2017, 37 (07): : 2458 - 2470
  • [3] Synthesis and evaluation of [11C]MMPIP as a potential radioligand for imaging of metabotropic glutamate 7 receptor in the brain
    Tomoteru Yamasaki
    Katsushi Kumata
    Joji Yui
    Masayuki Fujinaga
    Kenji Furutsuka
    Akiko Hatori
    Lin Xie
    Masanao Ogawa
    Nobuki Nengaki
    Kazunori Kawamura
    Ming-Rong Zhang
    [J]. EJNMMI Research, 3
  • [4] Synthesis and evaluation of [11C] MMPIP as a potential radioligand for imaging of metabotropic glutamate 7 receptor in the brain
    Yamasaki, Tomoteru
    Kumata, Katsushi
    Yui, Joji
    Fujinaga, Masayuki
    Furutsuka, Kenji
    Hatori, Akiko
    Xie, Lin
    Ogawa, Masanao
    Nengaki, Nobuki
    Kawamura, Kazunori
    Zhang, Ming-Rong
    [J]. EJNMMI RESEARCH, 2013, 3
  • [5] LABELING OF SP203 WITH CARBON-11 FOR EVALUATION AS AN MGLUR5 RADIOLIGAND IN MONKEY WITH PET
    Simeon, F. G.
    Hong, J.
    Liow, J.
    Gladding, R.
    Innis, R. B.
    Pike, V. W.
    [J]. JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2009, 52 : S387 - S387
  • [6] Radiation dosimetry and human brain imaging of [18F]SP203:: A PET radioligand for the metabotropic glutamate mG1uR5 receptor
    Brown, Amira K.
    Simeon, F.
    Liow, J. S.
    Zoghbi, S.
    Kimara, Y.
    Fujita, M.
    MoZley, P. D.
    Pike, V.
    Innis, R. B.
    [J]. NEUROIMAGE, 2008, 41 : T178 - T178
  • [7] Evaluation of [11C]LY2428703: A new radioligand for subtype 1 metabotropic glutamate receptors
    Zanotti-Fregonara, Paolo
    Liow, Jeih-San
    Zoghbi, Sami
    Barth, Vanessa
    Nisenbaum, Eric
    Rhoads, Emily
    Kuklish, Steven
    Morse, Cheryl
    Pike, Victor
    Innis, Robert
    [J]. JOURNAL OF NUCLEAR MEDICINE, 2012, 53
  • [8] Radiosynthesis of [11C]sotrastaurin and evaluation as a PET radioligand for imaging brain PKC in monkey
    Singh, Prachi
    Cai, Lisheng
    Morse, Cheryl
    Gladding, Robert
    Fujita, Masahiro
    Innis, Robert
    Pike, Victor
    [J]. JOURNAL OF NUCLEAR MEDICINE, 2014, 55
  • [9] The metabotropic glutamate receptor 5 radioligand [11C]AZD9272 identifies unique binding sites in primate brain
    Varnas, Katarina
    Jureus, Anders
    Finnema, Sjoerd J.
    Johnstrom, Peter
    Raboisson, Patrick
    Amini, Nahid
    Takano, Akihiro
    Stepanov, Vladimir
    Halldin, Christer
    Farde, Lars
    [J]. NEUROPHARMACOLOGY, 2018, 135 : 455 - 463
  • [10] Synthesis and initial evaluation of [11C](R)-RWAY in monkey—a new, simply labeled antagonist radioligand for imaging brain 5-HT1A receptors with PET
    Julie A. McCarron
    Sami S. Zoghbi
    H. Umesha Shetty
    Eric S. Vermeulen
    Håkan V. Wikström
    Masanori Ichise
    Fumihiko Yasuno
    Christer Halldin
    Robert B. Innis
    Victor W. Pike
    [J]. European Journal of Nuclear Medicine and Molecular Imaging, 2007, 34 : 1670 - 1682
12345