Synaptic correlates of fear extinction in the amygdala

被引:0
|
作者
Taiju Amano
Cagri T Unal
Denis Paré
机构
[1] Center for Molecular and Behavioral Neuroscience,
[2] Rutgers,undefined
[3] The State University of New Jersey,undefined
来源
Nature Neuroscience | 2010年 / 13卷
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摘要
The mechanisms underlying fear extinction remain unclear. Here, the authors show that extinction enhances basolateral amygdala inputs about conditioned stimuli to intercalated cells, resulting in the inhibition of fear output central amygdala neurons. These changes required medial prefrontal activity during extinction training, but, once induced, could be expressed without prefrontal inputs.
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页码:489 / 494
页数:5
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