Reconstitution of clathrin-coated bud and vesicle formation with minimal components

被引:0
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作者
Philip N. Dannhauser
Ernst J. Ungewickell
机构
[1] Centre of Anatomy,Department of Cell Biology
[2] Hannover Medical School,undefined
来源
Nature Cell Biology | 2012年 / 14卷
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摘要
Clathrin-mediated endocytosis requires the generation of membrane curvature and subsequent formation of clathrin-coated vesicles. Using a cell-free system, Dannhauser and Ungewickell show that clathrin polymerization is capable of inducing membrane deformation and generating spherical vesicles.
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页码:634 / 639
页数:5
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