A CRISPR/Cas system mediates bacterial innate immune evasion and virulence

被引：0
|
作者：
Timothy R. Sampson
Sunil D. Saroj
Anna C. Llewellyn
Yih-Ling Tzeng
David S. Weiss
机构：
[1] Microbiology and Molecular Genetics Program,Department of Microbiology and Immunology
[2] Emory University,Division of Infectious Diseases, Department of Medicine
[3] Emory Vaccine Center,undefined
[4] Emory University,undefined
[5] Yerkes National Primate Research Center,undefined
[6] Emory University,undefined
[7] Emory University School of Medicine,undefined
来源：
Nature | 2013年 / 497卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The CRISPR/Cas system known to aid bacterial defences by targeting invading DNA can also act to evade eukaryotic defences through a different class of small RNAs downregulating an endogenous immunogenic bacterial lipoprotein.
引用
收藏
页码：254 / 257
页数：3
相关论文
共 50 条
  • [1] A CRISPR/Cas system mediates bacterial innate immune evasion and virulence
    Sampson, Timothy R.
    Saroj, Sunil D.
    Llewellyn, Anna C.
    Tzeng, Yih-Ling
    Weiss, David S.
    [J]. NATURE, 2013, 497 (7448) : 254 - +
  • [2] Correction: Corrigendum: A CRISPR/Cas system mediates bacterial innate immune evasion and virulence
    Timothy R. Sampson
    Sunil D. Saroj
    Anna C. Llewellyn
    Yih-Ling Tzeng
    David S. Weiss
    [J]. Nature, 2013, 501 : 262 - 262
  • [3] Author Correction: A CRISPR/Cas system mediates bacterial innate immune evasion and virulence
    Timothy R. Sampson
    Sunil D. Saroj
    Anna C. Llewellyn
    Yih-Ling Tzeng
    David S. Weiss
    [J]. Nature, 2019, 570 : E30 - E31
  • [4] A CRISPR/Cas system mediates bacterial innate immune evasion and virulence (vol 497, pg 254, 2013)
    Sampson, Timothy R.
    Saroj, Sunil D.
    Llewellyn, Anna C.
    Tzeng, Yih-Ling
    Weiss, David S.
    [J]. NATURE, 2019, 570 (7760) : E30 - +
  • [5] A CRISPR/Cas system mediates bacterial innate immune evasion and virulence (vol 497, pg 254, 2013)
    Sampson, Timothy R.
    Saroj, Sunil D.
    Llewellyn, Anna C.
    Tzeng, Yih-Ling
    Weiss, David S.
    [J]. NATURE, 2013, 501 (7466) : 262 - 262
  • [6] Secreted Autotransporter Toxin (Sat) Mediates Innate Immune System Evasion
    Freire, Claudia A.
    Silva, Rosa M.
    Ruiz, Rita C.
    Pimenta, Daniel C.
    Bryant, Jack A.
    Henderson, Ian R.
    Barbosa, Angela S.
    Elias, Waldir P.
    [J]. FRONTIERS IN IMMUNOLOGY, 2022, 13
  • [7] Resistance is not futile: bacterial 'innate' and CRISPR-Cas 'adaptive' immune systems
    Fineran, Peter C.
    [J]. MICROBIOLOGY-SGM, 2019, 165 (08): : 834 - 841
  • [8] CRISPR-Cas system in regulation of immunity and virulence of bacterial pathogens
    Ahmed, Waqas
    Hafeez, Mian Abdul
    Ahmad, Rais
    Mahmood, Sammina
    [J]. GENE REPORTS, 2018, 13 : 151 - 157
  • [9] Bacteriophage genes that inactivate the CRISPR/Cas bacterial immune system
    Joe Bondy-Denomy
    April Pawluk
    Karen L. Maxwell
    Alan R. Davidson
    [J]. Nature, 2013, 493 : 429 - 432
  • [10] The bacterial CRISPR/Cas system as analog of the mammalian adaptive immune system
    Goren, Moran G.
    Yosef, Ido
    Edgar, Rotem
    Qimron, Udi
    [J]. RNA BIOLOGY, 2012, 9 (05) : 549 - 554
12345