Involvement of L-type calcium channels and mitochondria in post-tetanic potentiation: Is it a general rule for different types of synapses?

被引:0
|
作者
M. V. Storozhuk
S. M. Fredman
S. Yu. Ivanova
P. M. Balaban
P. G. Kostyuk
机构
[1] National Academy of Sciences of Ukraine,Bogomolets Institute of Physiology
[2] National Academy of Sciences of Ukraine,International Center of Molecular Physiology
[3] Meharry Medical College,undefined
[4] Institute of Higher Nervous Activity and Neurophysiology,undefined
来源
Neurophysiology | 2007年 / 39卷
关键词
synaptic plasticity; post-tetanic potentiation; mitochondria; L-type calcium channels;
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学科分类号
摘要
Our experiments and studies of a few other authors demonstrated that L-type calcium channels and mitochondria are involved in the induction of post-tetanic potentiation (PTP) in a number of preparations (Aplysia central nervous system, hippocampal cell cultures, crayfish neuromuscular junctions, etc.). We extend this conclusion on cortical synapses by the demonstration that inhibitors of mitochondrial Ca2+ uptake and release suppress PTP in rat neocortical cell cultures.
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页码:353 / 354
页数:1
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