Chronic opioid use after joint replacement surgery in seniors is associated with increased healthcare utilization and costs: a historical cohort study; [Association entre la consommation chronique d’opioïdes après une chirurgie de remplacement articulaire chez les personnes âgées et une augmentation de l’utilisation et des coûts des soins de santé : une étude de cohorte historique]

被引:0
|
作者
Johnson A. [1 ,3 ]
Milne B. [2 ]
Jamali N. [3 ]
Pasquali M. [3 ,4 ]
Gilron I. [2 ]
Mann S. [3 ,5 ]
Moore K. [3 ,6 ]
Graves E. [7 ]
Parlow J. [2 ]
机构
[1] Department of Public Health Sciences, Senior ICES Scientist, Queen’s University, Kingston, ON
[2] Department of Anesthesiology and Perioperative Medicine, Kingston Health Sciences Centre, Queen’s University, 76 Stuart Street, Kingston, K7L 2V7, ON
[3] Queen’s University, Kingston, ON
[4] Western University, London, ON
[5] Division of Orthopedic Surgery, Queen’s University, Kingston, ON
[6] Departments of Emergency and Family Medicine, Queen’s University, Kingston, ON
[7] Institute for Clinical Evaluative Sciences, Toronto, ON
关键词
analgesics; arthroplasty; economics; opioids; postoperative pain;
D O I
10.1007/s12630-022-02240-1
中图分类号
学科分类号
摘要
Purpose: Postoperative opioid use may be associated with increased healthcare utilization and costs. We sought to examine the relationship between duration of postoperative opioid prescriptions and healthcare costs and resource utilization in senior patients following hip and knee replacement. Methods: We conducted a historical cohort study evaluating postoperative opioid use and healthcare costs in patients over the age of 65 yr undergoing primary total hip or knee arthroplasty over a ten-year period from 1 April 2006 to 31 March 2016. The last follow-up date was 31 March 2017. We identified preoperative and postoperative opioid prescriptions, patient characteristics, and healthcare costs using deidentified Ontario administrative databases (Institute of Clinical Evaluative Sciences). Duration of postoperative opioid use was divided into four categories: short-term (1–90 days), prolonged (91–180 days), chronic (181–365 days), and undocumented. Results: The study included 49,638 hip and 85,558 knee replacement patients. Although the initial hospitalization accounted for the greatest cost in all patients, over the following year patients in the short-term opioid use group incurred the lowest average costs, and those in the chronic group incurred the highest (hip, CAD 17,528 vs CAD 26,736; knee, CAD 16,043 vs CAD 23,007), driven by increased healthcare resource utilization. Conclusion: Chronic opioid use after arthroplasty was associated with higher resource utilization and healthcare costs during the year following surgery. These results can be used to develop predictors of longer opioid use and higher costs. Further research is planned to determine whether recently implemented opioid reduction strategies can reduce healthcare resource utilization. © 2022, Canadian Anesthesiologists' Society.
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页码:963 / 973
页数:10
相关论文
共 23 条
  • [1] Long-term opioid use in seniors following hip and knee arthroplasty in Ontario: a historical cohort study; [Consommation à long terme d’opioïdes chez les personnes âgées à la suite d’une arthroplastie de la hanche ou du genou en Ontario : une étude de cohorte historique]
    Johnson A.
    Milne B.
    Pasquali M.
    Jamali N.
    Mann S.
    Gilron I.
    Moore K.
    Graves E.
    Parlow J.
    [J]. Canadian Journal of Anesthesia/Journal canadien d'anesthésie, 2022, 69 (8): : 934 - 944
  • [2] Low serum vitamin D levels are not associated with increased postoperative pain and opioid requirements: a historical cohort study [Des taux faibles de vitamine D sérique ne sont pas associés à une augmentation de la douleur postopératoire et des besoins en opioïdes: une étude de cohorte historique]
    Bose S.
    Khanna A.
    You J.
    Arora L.
    Qavi S.
    Turan A.
    [J]. Canadian Journal of Anesthesia/Journal canadien d'anesthésie, 2015, 62 (7): : 770 - 776
  • [3] A prospective observational study of persistent opioid use after complex foot and ankle surgery; [Étude observationnelle prospective de la consommation persistante d’opioïdes après une chirurgie complexe du pied et de la cheville]
    Verrier M.
    Niu S.
    Kroetch K.
    Buro K.
    Douglas C.
    Green J.
    Pedersen M.E.
    Dillane D.
    [J]. Canadian Journal of Anesthesia/Journal canadien d'anesthésie, 2022, 69 (8): : 945 - 952
  • [4] Opioid-sparing anesthesia and patient-reported outcomes after open gynecologic surgery: a historical cohort study; [Anesthésie avec épargne opioïde et issues rapportées par les patientes après une chirurgie gynécologique avec laparotomie : une étude de cohorte historique]
    Zorrilla-Vaca A.
    Ramirez P.T.
    Iniesta-Donate M.
    Lasala J.D.
    Wang X.S.
    Williams L.A.
    Meyer L.
    Mena G.E.
    [J]. Canadian Journal of Anesthesia/Journal canadien d'anesthésie, 2022, 69 (12): : 1477 - 1492
  • [5] Opioid prescribing and utilization patterns in patients having elective hip and knee arthroplasty: association between prescription patterns and opioid consumption; [Schémas de prescription et d’utilisation des opioïdes chez les patients bénéficiant d’une arthroplastie non urgente de la hanche et du genou : association entre ces schémas de prescription et la consommation d’opioïdes]
    Chan B.
    Ward S.
    Abdallah F.W.
    Jones C.
    Papachristos A.
    Chin K.
    Ladha K.S.
    Hare G.M.T.
    [J]. Canadian Journal of Anesthesia/Journal canadien d'anesthésie, 2022, 69 (8): : 953 - 962
  • [6] Hospital cost associated with anemia in elective colorectal surgery: a historical cohort study; [Les coûts hospitaliers associés à l’anémie lors d’une chirurgie colorectale non urgente: une étude de cohorte historique]
    Feng S.
    Greenberg J.
    Moloo H.
    Thavorn K.
    McIsaac D.I.
    [J]. Canadian Journal of Anesthesia/Journal canadien d'anesthésie, 2019, 66 (8): : 877 - 885
  • [7] Trends in opioid dispensing after common abdominal and orthopedic surgery procedures in British Columbia: a retrospective cohort analysis; [Tendances de la délivrance d’opioïdes après des interventions courantes de chirurgie abdominale et orthopédique en Colombie-Britannique : une analyse rétrospective de cohorte]
    Nann P.
    Nabavi N.
    Ziafat K.
    Preston R.
    Chau A.
    Krausz M.R.
    Schwarz S.K.W.
    Maclure M.
    [J]. Canadian Journal of Anesthesia/Journal canadien d'anesthésie, 2022, 69 (8): : 986 - 996
  • [8] Avoidable intensive care unit resource use and costs of unvaccinated patients with COVID-19: a historical population-based cohort study [Utilisation et coûts évitables des ressources des unités de soins intensifs pour les patients non vaccinés atteints de COVID-19 : une étude de cohorte historique basée sur la population]
    Bagshaw S.M.
    Abbott A.
    Beesoon S.
    Zuege D.J.
    Wasylak T.
    Manns B.
    Nguyen T.X.
    [J]. Canadian Journal of Anesthesia/Journal canadien d'anesthésie, 2022, 69 (11): : 1399 - 1404
  • [9] Association of intraoperative dexmedetomidine use with postoperative hypotension in unilateral hip and knee arthroplasties: a historical cohort study; [Association entre l’utilisation peropératoire de dexmédétomidine et l’hypotension postopératoire dans les arthroplasties unilatérales de la hanche et du genou : une étude de cohorte historique]
    Yang S.S.
    Gelinas C.
    Yim E.
    Li M.M.J.
    Kardash K.
    Zhang M.
    Lipes J.
    [J]. Canadian Journal of Anesthesia/Journal canadien d'anesthésie, 2022, 69 (12): : 1459 - 1470
  • [10] Prevalence of discordant elevations of state entropy and bispectral index in patients at amnestic sevoflurane concentrations: a historical cohort study; [Fréquence des élévations discordantes de l’entropie basale et de l’index bispectral chez les patients à des concentrations de sévoflurane provoquant l’amnésie : une étude de cohorte historique]
    Epstein R.H.
    Maga J.M.
    Mahla M.E.
    Schwenk E.S.
    Bloom M.J.
    [J]. Canadian Journal of Anesthesia/Journal canadien d'anesthésie, 2018, 65 (5): : 512 - 521