Long-term potentiation in awake mutant mice

被引:0
|
作者
M. L. Errington
T. V. P. Bliss
R. J. Morris
S. Laroche
S. Davis
机构
[1] National Institute for Medical Research,Division of Neurophysiology
[2] UMDS Guy's Hospital,Department of Experimental Pathology
[3] Neurobiologie de l'Apprentissage et de la Mémoire,undefined
[4] CNRS URA 1491,undefined
[5] Université de Paris Sud,undefined
来源
Nature | 1997年 / 387卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
The relationship between long-term potentiation (LTP) and spatial learning has been explored in a variety of genetically engineered mice with deletions of specific genes1. With few exceptions, LTP in these animals has been studied in the hippocampal slice preparation. The conditions required to elicit LTP in vitro, however, may not be comparable to those in the intact animal.
引用
收藏
页码:666 / 667
页数:1
相关论文
共 50 条
  • [1] Long-term potentiation in awake mutant mice
    Errington, ML
    Bliss, TVP
    Morris, RJ
    Laroche, S
    Davis, S
    [J]. NATURE, 1997, 387 (6634) : 666 - 667
  • [2] Compensation for PKMζ in long-term potentiation and spatial long-term memory in mutant mice
    Tsokas, Panayiotis
    Hsieh, Changchi
    Yao, Yudong
    Lesburgueres, Edith
    Wallace, Emma Jane Claire
    Tcherepanov, Andrew
    Jothianandan, Desingarao
    Hartley, Benjamin Rush
    Pan, Ling
    Rivard, Bruno
    Farese, Robert V.
    Sajan, Mini P.
    Bergold, Peter John
    Hernandez, Alejandro Ivan
    Cottrell, James E.
    Shouval, Harel Z.
    Fenton, Andre Antonio
    Sacktor, Todd Charlton
    [J]. ELIFE, 2016, 5
  • [3] Steel mutant mice are deficient in hippocampal learning but not long-term potentiation
    Motro, B
    Wojtowicz, JM
    Bernstein, A
    vanderKooy, D
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (05) : 1808 - 1813
  • [5] MODIFIED HIPPOCAMPAL LONG-TERM POTENTIATION IN PKC-GAMMA-MUTANT MICE
    ABELIOVICH, A
    CHEN, C
    GODA, Y
    SILVA, AJ
    STEVENS, CF
    TONEGAWA, S
    [J]. CELL, 1993, 75 (07) : 1253 - 1262
  • [6] Impaired cerebellar long-term potentiation in type I adenylyl cyclase mutant mice
    Storm, DR
    Hansel, C
    Hacker, B
    Parent, A
    Linden, DJ
    [J]. NEURON, 1998, 20 (06) : 1199 - 1210
  • [7] Altered behavior and long-term potentiation in type I adenylyl cyclase mutant mice
    Wu, Z.-L.
    Thomas, S. A.
    Villacres, E. C.
    Xia, Z.
    [J]. Proceedings of the National Academy of Sciences of the United States of America, 1600, 926
  • [8] HIPPOCAMPAL LONG-TERM POTENTIATION IS NORMAL IN HEME OXYGENASE-2 MUTANT MICE
    POSS, KD
    THOMAS, MJ
    EBRALIDZE, AK
    ODELL, TJ
    TONEGAWA, S
    [J]. NEURON, 1995, 15 (04) : 867 - 873
  • [9] LONG-TERM POTENTIATION IN MICE LACKING SYNAPSINS
    SPILLANE, DM
    ROSAHL, TW
    SUDHOF, TC
    MALENKA, RC
    [J]. NEUROPHARMACOLOGY, 1995, 34 (11) : 1573 - 1579
  • [10] HIPPOCAMPAL LONG-TERM POTENTIATION IN HYPERPROLINEMIC MICE
    LARSON, J
    LYNCH, GS
    DAVIS, JL
    [J]. MEDICAL SCIENCE RESEARCH-BIOCHEMISTRY, 1987, 15 (11-12): : 635 - 635