DNA electrochemical sensor based on an adduct of single-walled carbon nanotubes and ferrocene

被引：0
|
作者：
Xiaoying Yang
Yanhong Lu
Yanfeng Ma
Zunfeng Liu
Feng Du
Yongsheng Chen
机构：
[1] Tianjin Medical University,School of Pharmaceutical Sciences
[2] Institute of Polymer Chemistry,Center for Nanoscale Science and Technology and Key Laboratory for Functional Polymer Materials
[3] Nankai University,undefined
来源：
Biotechnology Letters | 2007年 / 29卷
关键词：
DNA; Electrochemistry; Immobilization; Single-walled carbon nanotubes;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A novel electrochemical sandwich-type gene sensing system was designed by using a DNA probe (DNA-probe1) immobilized on a gold electrode, the target DNA, and another DNA probe (DNA-probe2) conjugated on a single-walled carbon nanotubes/ferrocene (Fc–SWNT) adduct. In this sandwich-type gene-sensing electrode, the Fc–SWNT adduct could significantly amplify the electrochemical response of the reduction of H2O2. The target DNA could be detected selectively and sensitively based on the much enhanced electrochemical catalytic property of the Fc–SWNT adduct toward H2O2 reduction.
引用
收藏
页码：1775 / 1779
页数：4
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