SUMO amplifies TGF-β signalling

被引：0
|
作者：
Kohei Miyazono
Yuto Kamiya
Keiji Miyazawa
机构：
[1] Kohei Miyazono,Yuto Kamiya and Keiji Miyazawa are in the Department of Molecular Pathology
[2] Graduate School of Medicine,undefined
[3] University of Tokyo,undefined
[4] Hongo 7-3-1,undefined
[5] Bunkyo-ku,undefined
[6] Tokyo 113-0033,undefined
[7] Japan. miyazono-ind@umin.ac.jp mm66211@mail.ecc.u-tokyo.ac.jp keiji-miyazawa@umin.ac.jp,undefined
来源：
Nature Cell Biology | 2008年 / 10卷
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摘要：
Transforming growth factor-β (TGF-β) stimulates phosphorylation of TGF-β type I receptor. This receptor is now shown to be sumoylated, leading to enhanced activation and modulation of the downstream Smad signalling pathway.
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页码：635 / 637
页数：2
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