Latozinemab, a novel progranulin-elevating therapy for frontotemporal dementia

被引:0
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作者
Michael Kurnellas
Ananya Mitra
Tina Schwabe
Robert Paul
Andrew E. Arrant
Erik D. Roberson
Michael Ward
Felix Yeh
Hua Long
Arnon Rosenthal
机构
[1] Alector,Center for Neurodegeneration and Experimental Therapeutics, Alzheimer’s Disease Center, and Evelyn F. McKnight Brain Institute, Departments of Neurology and Neurobiology
[2] Inc.,undefined
[3] University of Alabama at Birmingham,undefined
[4] Neuron23,undefined
[5] Nine Square Therapeutics,undefined
[6] Inc.,undefined
[7] Genentech,undefined
关键词
Frontotemporal dementia; Latozinemab; Neuroprotection; Phase 1 clinical trial; Pharmacodynamics; Pharmacokinetics; Progranulin; Safety; Sortilin;
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