New Synthesis of Pyrano[4,3-d]pyrazolo[3,4-b]pyridines

被引：0
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作者：
S. N. Sirakanyan
E. K. Hakobyan
A. A. Hovakimyan
机构：
[1] National Academy of Sciences of Armenia,Mndzhoyan Institute of Fine Organic Chemistry, Scientific Technological Center of Organic and Pharmaceutical Chemistry
来源：
Russian Journal of Organic Chemistry | 2018年 / 54卷
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摘要：
A new efficient method has been developed for the synthesis of highly biologically active pyrano-[4,3-d]pyrazolo[3,4-b]pyridines on the basis of Smiles rearrangement of ethyl [(8-alkyl(aryl)-5-cyano-3,3-dimethyl-3,4-dihydro-1H-pyrano[3,4-c]pyridin-6-yl)oxy]acetates. Intermediate acetohydrazides have also been isolated. The proposed procedure is advantageous due to the possibility of avoiding experimentally difficult chlorination stage.
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页码：929 / 932
页数：3
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