Germline BRCA2 mutations in men with breast cancer

被引：0
|
作者：
E Mavraki
IC Gray
DT Bishop
NK Spurr
机构：
[1] Imperial Cancer Research Fund,
[2] Genetic Epidemiology,undefined
[3] St James's Hospital,undefined
来源：
British Journal of Cancer | 1997年 / 76卷
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摘要：
Breast cancer in men is rare and is clearly due in some cases to an inherited predisposition. A total of 28 male breast cancer patients were tested for BRCA2 mutations; two frameshifts and one putative missense mutation were identified. One of the frameshifts was detected in the same position as a mutation estimated to be responsible for 40% of all male breast cancer cases in Iceland.
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页码：1428 / 1431
页数：3
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