Synthesis of 2-(3-furyl)-1H-benzimidazoles from 2-phenacyl-1H- benzimidazoles

被引：0
|
作者：
Dzvinchuk I.B. [1 ]
Lozinskii M.O. [1 ]
机构：
[1] Institute of Organic Chemistry, National Academy of Sciences of Ukraine
来源：
Chem. Heterocycl. Compd. | 2007年 / 11卷 / 1390-1396期
关键词：
Benzimidazoles; C-alkylation; Cyclocondensation; Furans; Phenacyl bromides; Selectivity;
D O I：
10.1007/s10593-007-0215-6
中图分类号：
学科分类号：
摘要：
C-Alkylation at the active methylene group of 2-phenacyl-1H-benzimidazoles with phenacyl bromides proceeds highly selectively with the formation of the corresponding 1,4-diketones, which on heating with hydrochloric acid are cyclized with the formation of the previously unknown 2-(2,5-diaryl-3-furyl)-1H- benzimidazoles. © 2007 Springer Science+Business Media, Inc.
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页码：1390 / 1396
页数：6
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