Cancer signaling: when phosphorylation meets methylation

被引：0
|
作者：
Haoqiang Ying
Ronald A DePinho
机构：
[1] University of Texas MD Anderson Cancer Center,Department of Molecular and Cellular Oncology
[2] University of Texas MD Anderson Cancer Center,Departments of Cancer Biology
来源：
Cell Research | 2014年 / 24卷
关键词：
D O I：
暂无
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学科分类号：
摘要：
The propagation of kinase-mediated phosphorylation signals is central to the oncogenic activity of the RAS-MAPK pathway in human cancers. A recent study shows that protein lysine methylation controls the phosphorylation status of a key component of the RAS-MAPK pathway to enable oncogenic KRAS in cancer progression.
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页码：1282 / 1283
页数：1
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