The aldehyde dehydrogenase gene superfamily resource center.

被引:0
|
作者
Black W. [1 ]
Vasiliou V. [1 ]
机构
[1] Molecular Toxicology and Environmental Health Sciences Program, Department of Pharmaceutical Sciences, University of Colorado Denver, Aurora, 80045, CO
基金
美国国家卫生研究院;
关键词
Genomic database; aldehyde dehydrogenase; ALDH; nomenclature; gene superfamily;
D O I
10.1186/1479-7364-4-2-136
中图分类号
学科分类号
摘要
The website www.aldh.org is a publicly available database for nomenclature and functional and molecular sequence information for members of the aldehyde dehydrogenase (ALDH) gene superfamily for animals, plants, fungi and bacteria. The site has organised gene-specific records. It provides synopses of ALDH gene records, marries trivial terms to correct nomenclature and links global accession identifiers with source data. Server-side alignment software characterises the integrity of each sequence relative to the latest genomic assembly and provides identifier-specific detail reports, including a graphical presentation of the transcript's exon-intron structure, its size, coding sequence, genomic strand and locus. Also included are a summary of substrates, inhibitors and enzyme kinetics. The site provides reference lists and is designed to facilitate data mining by interested investigators.
引用
收藏
页码:136 / 142
页数:6
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