Applying next-generation sequencing to pancreatic cancer treatment

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作者
Elaine R. Mardis
机构
[1] The Genome Institute,
[2] Washington University School of Medicine,undefined
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Pancreatic cancer is a highly lethal malignancy that presents multiple technical challenges for genomic studies. Next-generation sequencing and its applications have proven successful in other tumour types, and could be useful for studying pancreatic cancer. This Review outlines pancreatic cancer genomics to date, the genomic discovery applications enabled by next-generation sequencing technology and analysis, and a synthesis of the two areas that might be suggestive of a path forward.
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页码:477 / 486
页数:9
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