Combined phototherapy in anti-cancer treatment: therapeutics design and perspectives

被引：36

作者：

Tran T.H. ^{[1
]}

Thapa R.K. ^{[1
]}

Nguyen H.T. ^{[1
]}

Pham T.T. ^{[1
]}

Ramasamy T. ^{[1
]}

Kim D.S. ^{[2
]}

Yong C.S. ^{[1
]}

Kim J.O. ^{[1
]}

Choi H.-G. ^{[2
]}

机构：

[1] College of Pharmacy, Yeungnam University, 214-1, Dae-Dong, Gyeongsan

[2] College of Pharmacy & Institute of Pharmaceutical Science and Technology, Hanyang University, 55, Hanyangdaehak-ro, Sangnok-gu, Ansan

来源：

Journal of Pharmaceutical Investigation | 2016年 / 46卷 / 6期

关键词：

Hyperthermia; Nanocarriers; Photodynamic; Photosensitiser; Photothermal;

D O I：

10.1007/s40005-016-0272-x

中图分类号：

学科分类号：

摘要：

Photodynamic (PDT) and photothermal (PTT) therapy are proven effective strategies for the treatment of cancer. PDT, a photochemistry-based therapy, utilises light energy based photosensitiser for the production of cytotoxic species via electron transfer to biological substrates and potential excitation or energy transfer to molecular oxygen. On the other hand, PTT utilises substances that can convert light energy into heat for efficient tumour ablation. This review provides an insight into the current research investigations of different nanocarriers utilising the synergistic effects of PTT and PDT for anticancer therapy. © 2016, The Korean Society of Pharmaceutical Sciences and Technology.

引用

页码：505 / 517

页数：12

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