A novel three-component reaction designed by the combinatorial method: Heteroarenes, isothiocyanates and isocyanides

被引:0
|
作者
Maxim A. Mironov
Sergey S. Maltsev
Vladimir S. Mokrushin
Vasiliy A. Bakulev
机构
[1] Urals State Technical University,Department of Technology of Organic Synthesis (TOSLab)
来源
Molecular Diversity | 2005年 / 9卷
关键词
combinatorial chemistry; isocyanides; isoquinolines; multicomponent reactions; phthalazines;
D O I
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中图分类号
学科分类号
摘要
The novel three-component reaction of isoquinoline with isothiocyanates and isocyanides leads to a variety of new imidazoisoquinolines. The zwitterionic ground state of these new ring systems is established by means of NMR and X-ray analysis. Use of phthalazine instead of isoquinoline gives access to imidazole annulated phthalazines.
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页码:221 / 227
页数:6
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