Antibiotics for treatment of resistant gram-positive coccal infections

被引:8
|
作者
Hossam Al-Tatari
Nahed Abdel-Haq
Pimpanada Chearskul
Basim Asmar
机构
[1] Wayne State University School of Medicine,Carman and Ann Adams Department of Pediatrics
[2] Children's Hospital of Michigan,Division of Infectious Diseases
关键词
Vancomycin; Gram-positive; Bacterial infections; Antibacterial agents;
D O I
10.1007/BF02825827
中图分类号
学科分类号
摘要
Vancomycin is considered the workhorse for the treatment of most drug-resistant gram-positive bacterial infections. However, concerns have been raised regarding the increasing rates of vancomycin-resistant enterococci and the clinical shortcomings of vancomycin in the treatment of invasiveStaphylococcus aureus infections. Resources have been committed to the development of antimicrobial agents with activity against these organisms. This review will focus on the newer antibacterial agents that have been developed for the treatment of resistant gram-positive pathogens. Included in this review are the agents: quinupristin-dalfopristin, linezolid, daptomycin, telithromycin, and tigecycline.
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页码:323 / 334
页数:11
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