Oscillatory flow reactors for synthetic chemistry applications

被引:0
|
作者
Pauline Bianchi
Jason D. Williams
C. Oliver Kappe
机构
[1] University of Graz,Institute of Chemistry
[2] NAWI Graz,Center for Continuous Flow Synthesis and Processing (CC FLOW)
[3] Research Center Pharmaceutical,undefined
[4] Engineering (RCPE),undefined
来源
Journal of Flow Chemistry | 2020年 / 10卷
关键词
Oscillatory flow; Multiphasic reactions; Solid handling; Liquid-liquid reactions; Process intensification; Plug flow reactors;
D O I
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中图分类号
学科分类号
摘要
Oscillatory flow reactors (OFRs) superimpose an oscillatory flow to the net movement through a flow reactor. OFRs have been engineered to enable improved mixing, excellent heat- and mass transfer and good plug flow character under a broad range of operating conditions. Such features render these reactors appealing, since they are suitable for reactions that require long residence times, improved mass transfer (such as in biphasic liquid-liquid systems) or to homogeneously suspend solid particles. Various OFR configurations, offering specific features, have been developed over the past two decades, with significant progress still being made. This review outlines the principles and recent advances in OFR technology and overviews the synthetic applications of OFRs for liquid-liquid and solid-liquid biphasic systems.
引用
收藏
页码:475 / 490
页数:15
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