A sulfonate relay revealed

被引：0
|
作者：
Steven G. Van Lanen
机构：
[1] College of Pharmacy University of Kentucky,Steven G. Van Lanen is at the Department of Pharmaceutical Sciences
[2] Lexington,undefined
[3] Kentucky,undefined
[4] USA.,undefined
来源：
Nature Chemical Biology | 2013年 / 9卷
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摘要：
Biological sulfonate incorporation is mediated by 3′-phosphoadenosine-5′-phosphosulfate–dependent sulfotransferases and, to a lesser extent, arylsulfate sulfotransferases. An unusual two-enzyme strategy for sulfonate mobilization involving both types of sulfotransferases has been revealed during antibiotic biosynthesis, which uses a new polyketide as the sulfonate shuttle.
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页码：602 / 603
页数：1
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