Adipose stem cell niche reprograms the colorectal cancer stem cell metastatic machinery

被引：0

作者：

Simone Di Franco

Paola Bianca

Davide Stefano Sardina

Alice Turdo

Miriam Gaggianesi

Veronica Veschi

Annalisa Nicotra

Laura Rosa Mangiapane

Melania Lo Iacono

Irene Pillitteri

Sander van Hooff

Federica Martorana

Gianmarco Motta

Eliana Gulotta

Vincenzo Luca Lentini

Emanuele Martorana

Micol Eleonora Fiori

Salvatore Vieni

Maria Rita Bongiorno

Giorgio Giannone

Dario Giuffrida

Lorenzo Memeo

Lorenzo Colarossi

Marzia Mare

Paolo Vigneri

Matilde Todaro

Ruggero De Maria

Jan Paul Medema

Giorgio Stassi

机构：

[1] University of Palermo,Department of Surgical Oncological and Stomatological Sciences (DICHIRONS)

[2] University of Palermo,Department of Health Promotion Sciences, Internal Medicine and Medical Specialties (PROMISE)

[3] Laboratory for Experimental Oncology and Radiobiology,Department of Clinical and Experimental Medicine, A.O.U. Policlinico

[4] Center for Experimental and Molecular Medicine,Vittorio Emanuele, Division of Medical Oncology

[5] Cancer Center Amsterdam,Department of Oncology and Molecular Medicine

[6] Amsterdam UMC,Department of Experimental Oncology

[7] University of Amsterdam,Department of Clinical and Experimental Medicine

[8] University of Catania,Department of Clinical and Experimental Medicine, A.O.U. Policlinico

[9] Reconstructive Plastic Surgery,Vittorio Emanuele, Center of Experimental Oncology and Hematology

[10] ARNAS Ospedali Civico Di Cristina e Benfratelli,undefined

[11] Pathology Unit,undefined

[12] Ospedali Riuniti Villa Sofia-Cervello,undefined

[13] IOM (Mediterranean Institute of Oncology) Ricerca,undefined

[14] Viagrande,undefined

[15] Istituto Superiore di Sanità,undefined

[16] Mediterranean Institute of Oncology,undefined

[17] Viagrande,undefined

[18] University of Messina,undefined

[19] “G.Martino” Hospital,undefined

[20] University of Catania,undefined

[21] Istituto di Patologia Generale,undefined

[22] Università Cattolica del Sacro Cuore,undefined

[23] Fondazione Policlinico Universitario “A. Gemelli” - I.R.C.C.S,undefined

[24] Oncode Institute,undefined

[25] Amsterdam UMC,undefined

[26] University of Amsterdam,undefined

来源：

Nature Communications | / 12卷

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摘要：

Obesity is a strong risk factor for cancer progression, posing obesity-related cancer as one of the leading causes of death. Nevertheless, the molecular mechanisms that endow cancer cells with metastatic properties in patients affected by obesity remain unexplored.

引用

共 50 条

[1] Adipose stem cell niche reprograms the colorectal cancer stem cell metastatic machinery
Di Franco, Simone
Bianca, Paola
Sardina, Davide Stefano
Turdo, Alice
Gaggianesi, Miriam
Veschi, Veronica
Nicotra, Annalisa
Mangiapane, Laura Rosa
Lo Iacono, Melania
Pillitteri, Irene
van Hooff, Sander
Martorana, Federica
Motta, Gianmarco
Gulotta, Eliana
Lentini, Vincenzo Luca
Martorana, Emanuele
Fiori, Micol Eleonora
Vieni, Salvatore
Bongiorno, Maria Rita
Giannone, Giorgio
Giuffrida, Dario
Memeo, Lorenzo
Colarossi, Lorenzo
Mare, Marzia
Vigneri, Paolo
Todaro, Matilde
De Maria, Ruggero
Medema, Jan Paul
Stassi, Giorgio
NATURE COMMUNICATIONS, 2021, 12 (01)
[2] Cancer Stem Cell Niche in Colorectal Cancer and Targeted Therapies
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Cui, Guihua
Yu, Bo
Sun, Meiyan
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CURRENT PHARMACEUTICAL DESIGN, 2020, 26 (17) : 1979 - 1993
[3] Regulation of Cancer Stem Cells by Stem Cell Niche
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[5] Cancer Stem Cell Niche: The Place to Be
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[6] Donor cell leukemia: insight into cancer stem cells and the stem cell niche
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BLOOD, 2007, 109 (07) : 2688 - 2692
[7] Prolactin hormone signaling promotes cancer stem cell niche and migration in colorectal cancer
Neradugomma, Naveen K.
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CANCER RESEARCH, 2012, 72
[8] Hemopoietic stem cell lodgement in the stem cell niche
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EXPERIMENTAL HEMATOLOGY, 2004, 32 (07) : 53 - 53
[9] Stem cell regulation by the hematopoietic stem cell niche
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CELL CYCLE, 2005, 4 (10) : 1353 - 1355
[10] The stem cell niche
Raheem, A.
EUROPEAN JOURNAL OF MEDICAL RESEARCH, 2009, 14 : 143 - 143

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