An inverse relationship to germline transcription defines centromeric chromatin in C. elegans

被引：0

作者：

Reto Gassmann

Andreas Rechtsteiner

Karen W. Yuen

Andrew Muroyama

Thea Egelhofer

Laura Gaydos

Francie Barron

Paul Maddox

Anthony Essex

Joost Monen

Sevinc Ercan

Jason D. Lieb

Karen Oegema

Susan Strome

Arshad Desai

机构：

[1] Ludwig Institute for Cancer Research and Department of Cellular & Molecular Medicine University of California San Diego,Department of Molecular Cell and Developmental Biology

[2] University of California Santa Cruz,Department of Biology

[3] Carolina Center for Genome Sciences and Lineberger Comprehensive Cancer Center,undefined

[4] University of North Carolina at Chapel Hill,undefined

[5] Present addresses: School of Biological Sciences,undefined

[6] the University of Hong Kong,undefined

[7] Pokfulam,undefined

[8] Hong Kong (K.W.Y.); Department of Craniofacial Biology,undefined

[9] University of Colorado,undefined

[10] Health Sciences Center,undefined

[11] Aurora,undefined

[12] Colorado 80045,undefined

[13] USA (F.B.); Institute for Research in Immunology and Cancer,undefined

[14] Department of Pathology and Cell Biology,undefined

[15] University of Montreal,undefined

[16] Montreal,undefined

[17] Quebec H3C 3J7,undefined

[18] Canada (P.M.); The Salk Institute for Biological Studies,undefined

[19] San Diego,undefined

[20] California 92186,undefined

[21] USA (A.E.); Department of Neurobiology and Behavior,undefined

[22] Cornell University,undefined

[23] Ithaca,undefined

[24] New York 14853,undefined

[25] USA (J.M.).,undefined

来源：

Nature | 2012年 / 484卷

关键词：

D O I：

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中图分类号：

学科分类号：

摘要：

Centromere identity is thought to be epigenetically propagated by stable inheritance of nucleosomes containing the histone variant CENP-A; the authors propose a different model here in which germline transcription defines the genomic regions that exclude CENP-A incorporation during embryogenesis in the holocentric worm Caenorhabditis elegans.

引用

页码：534 / 537

页数：3

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