Prediction of HIV-1 protease cleavage site from octapeptide sequence information using selected classifiers and hybrid descriptors

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作者
Emmanuel Onah
Philip F. Uzor
Ikenna Calvin Ugwoke
Jude Uche Eze
Sunday Tochukwu Ugwuanyi
Ifeanyi Richard Chukwudi
Akachukwu Ibezim
机构
[1] University of Nigeria,Department of Pharmaceutical and Medicinal Chemistry
[2] University of Nigeria,Department of Pharmaceutical Microbiology and Biotechnology
[3] University of Nigeria,Department of Clinical Pharmacy and Pharmacy Management
[4] University of Nigeria,Department of Pharmaceutical Technology and Industrial Pharmacy
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HIV-1 protease; Stratified 10-fold CV; Machine learning; Cleavage site; Octapeptide sequence; Amino acid binary profile; Physicochemical properties; Bond composition; Numerical descriptors;
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