Development of small-molecule inhibitors targeting adipose triglyceride lipase

被引：0
|
作者：
Nicole Mayer
Martina Schweiger
Matthias Romauch
Gernot F Grabner
Thomas O Eichmann
Elisabeth Fuchs
Jakov Ivkovic
Christoph Heier
Irina Mrak
Achim Lass
Gerald Höfler
Christian Fledelius
Rudolf Zechner
Robert Zimmermann
Rolf Breinbauer
机构：
[1] Institute of Organic Chemistry,
[2] Graz University of Technology,undefined
[3] Institute of Molecular Biosciences,undefined
[4] University of Graz,undefined
[5] Institute of Pathology,undefined
[6] Medical University of Graz,undefined
[7] Diabetes Research Unit,undefined
[8] Novo Nordisk A/S,undefined
来源：
Nature Chemical Biology | 2013年 / 9卷
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学科分类号：
摘要：
A competitive inhibitor of the lipase ATGL reduces the availability of adipocyte fatty acids, causing insulin resistance in insulin-sensitive tissues.[graphic not available: see fulltext]
引用
收藏
页码：785 / 787
页数：2
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