Embryonic stem cell–specific microRNAs promote induced pluripotency

被引：0
|
作者：
Robert L Judson
Joshua E Babiarz
Monica Venere
Robert Blelloch
机构：
[1] The Eli and Edythe Broad Center of Regeneration Medicine and Stem Cell Research,and Department of Urology
[2] Center for Reproductive Sciences,undefined
[3] University of California,undefined
[4] San Francisco,undefined
来源：
Nature Biotechnology | 2009年 / 27卷
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摘要：
Judson et al. show that microRNAs specific to mouse embryonic stem cells can substitute for the reprogramming factor cMyc in the generation of induced pluripotent stem cells. The development of reprogramming methods that do not rely on transgenes may facilitate clinical translation of this technology.
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页码：459 / 461
页数：2
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