High risk genes predisposing to prostate cancer development—do they exist?

被引：0
|
作者：
R Singh
RA Eeles
F Durocher
J Simard
S Edwards
M Badzioch
Z Kote-Jarai
D Teare
D Ford
D Dearnaley
A Ardern-Jones
A Murkin
A Dowe
R Shearer
J Kelly
F Labrie
D Easton
SA Narod
PN Tonin
WD Foulkes
机构：
[1] Institute of Cancer Research,Department of Medicine
[2] Royal Marsden NHS Trust,Division of Medical Genetics
[3] Laboratory of Molecular Endocrinology,undefined
[4] CHUL Research Center,undefined
[5] MD Anderson Cancer Centre,undefined
[6] CRC Genetic Epidemiology Unit,undefined
[7] Strangeways Research Laboratories,undefined
[8] Centre for Research in Women's Health,undefined
[9] Montreal General Hospital,undefined
[10] Box 35 7720,undefined
[11] University of Washington Medical Center,undefined
[12] Seattle,undefined
来源：
Prostate Cancer and Prostatic Diseases | 2000年 / 3卷
关键词：
prostate cancer; genetics; high risk genes; low risk genes;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
There is evidence for genetic predisposition to prostate cancer. However, prostate cancer genes have been more difficult to find than genes for some of the other common cancers, such as breast and colon cancer. The reasons for this are discussed in this article and it is now becoming clear that prostate cancer is probably due to multiple genes, many of which are moderate or low penetrance. The advances in the Human Genome Project and technology, especially that of robotics, will help to overcome these problems.
引用
收藏
页码：241 / 247
页数：6
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