Pro-proliferative and inflammatory signaling converge on FoxO1 transcription factor in pulmonary hypertension

被引:0
|
作者
Rajkumar Savai
Hamza M Al-Tamari
Daniel Sedding
Baktybek Kojonazarov
Christian Muecke
Rebecca Teske
Mario R Capecchi
Norbert Weissmann
Friedrich Grimminger
Werner Seeger
Ralph Theo Schermuly
Soni Savai Pullamsetti
机构
[1] Max-Planck-Institute for Heart and Lung Research,Department of Lung Development and Remodeling
[2] member of the German Center for Lung Research (DZL),Department of Internal Medicine
[3] Universities of Giessen and Marburg Lung Center (UGMLC),Department of Molecular Cardiology
[4] member of the DZL,Department of Cardiology and Angiology
[5] Justus-Liebig University,Department of Human Genetics
[6] University Clinic of Giessen and Marburg,undefined
[7] Hannover Medical School,undefined
[8] University of Utah School of Medicine,undefined
来源
Nature Medicine | 2014年 / 20卷
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学科分类号
摘要
Activation of the transcription factor FoxO1 ameliorates vascular remodeling in pulmonary hypertension, pointing to a potential new therapeutic strategy for this disease.
引用
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页码:1289 / 1300
页数:11
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