Hyperglycemia induces PFKFB3 overexpression and promotes malignant phenotype of breast cancer through RAS/MAPK activation

被引：0
|
作者：
Xiao Cheng
Xiupeng Jia
Chunnian Wang
Shangyan Zhou
Jiayi Chen
Lei Chen
Jinping Chen
机构：
[1] Ningbo Clinical Pathology Diagnosis Center,Department of Histopathology
[2] Ningbo Clinical Pathology Diagnosis Center,Department of Experimental Pathology
[3] Ningbo Clinical Pathology Diagnosis Center,Department of Cytopathology
来源：
World Journal of Surgical Oncology | / 21卷
关键词：
PFKFB3; miR-26; RAS/MAPK; Hyperglycemia; Breast cancer;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] Hyperglycemia induces PFKFB3 overexpression and promotes malignant phenotype of breast cancer through RAS/MAPK activation
    Cheng, Xiao
    Jia, Xiupeng
    Wang, Chunnian
    Zhou, Shangyan
    Chen, Jiayi
    Chen, Lei
    Chen, Jinping
    WORLD JOURNAL OF SURGICAL ONCOLOGY, 2023, 21 (01)
  • [2] Sonic hedgehog stimulates glycolysis and proliferation of breast cancer cells: Modulation of PFKFB3 activation
    Ge, Xin
    Lyu, Pengwei
    Gu, Yuanting
    Li, Lin
    Li, Jingruo
    Wang, Yan
    Zhang, Linfeng
    Fu, Chao
    Cao, Zhang
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2015, 464 (03) : 862 - 868
  • [3] Positive regulation of PFKFB3 by PIM2 promotes glycolysis and paclitaxel resistance in breast cancer
    Lu, Chao
    Qiao, Pengyun
    Sun, Yonghong
    Ren, Chune
    Yu, Zhenhai
    CLINICAL AND TRANSLATIONAL MEDICINE, 2021, 11 (04):
  • [4] Overexpression of miR-206 suppresses glycolysis, proliferation and migration in breast cancer cells via PFKFB3 targeting
    Ge, Xin
    Lyu, Pengwei
    Cao, Zhang
    Li, Jingruo
    Guo, Guangcheng
    Xia, Wanjun
    Gu, Yuanting
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2015, 463 (04) : 1115 - 1121
  • [5] PFKFB3 potentially contributes to paclitaxel resistance in breast cancer cells through TLR4 activation by stimulating lactate production
    Ge, X.
    Cao, Z.
    Gu, Y.
    Wang, F.
    Li, J.
    Han, M.
    Xia, W.
    Yu, Z.
    Lyu, P.
    CELLULAR AND MOLECULAR BIOLOGY, 2016, 62 (06) : 119 - 125
  • [6] Overexpression of Derlin 3 is associated with malignant phenotype of breast cancer cells
    Shibata, Masahiro
    Kanda, Mitsuro
    Tanaka, Haruyoshi
    Umeda, Shinichi
    Miwa, Takashi
    Shimizu, Dai
    Hayashi, Masamichi
    Inaishi, Takahiro
    Miyajima, Noriyuki
    Adachi, Yayoi
    Takano, Yuko
    Nakanishi, Kenichi
    Takeuchi, Dai
    Noda, Sumiyo
    Kodera, Yasuhiro
    Kikumori, Toyone
    ONCOLOGY REPORTS, 2017, 38 (03) : 1760 - 1766
  • [7] Pfkfb3 inhibition significantly decreases endocrine-resistant breast cancer growth and induces necroptotic cell death
    Jones, Brandon C.
    Sengupta, Surojeet
    Sevigny, Catherine M.
    Jin, Lu
    Pohlmann, Paula R.
    Shajahan-Haq, Ayesha
    Clarke, Robert
    CANCER RESEARCH, 2022, 82 (04)
  • [8] ADAM17 promotes breast cancer cell malignant phenotype through EGFR-PI3K-AKT activation
    Zheng, Xuguang
    Jiang, Feng
    Katakowski, Mark
    Zhang, Zheng Gang
    Lu, Qing-e
    Chopp, Michael
    CANCER BIOLOGY & THERAPY, 2009, 8 (11) : 1045 - 1054
  • [9] MARK4 promotes the malignant phenotype of gastric cancer through the MAPK/ERK signaling pathway
    Ma, Fubin
    Yao, Jibin
    Niu, Xingdong
    Zhang, Junrui
    Shi, Donghai
    Da, Mingxu
    PATHOLOGY RESEARCH AND PRACTICE, 2024, 261
  • [10] Circulating visfatin promotes malignant cancer behavior through activation of STAT3 signaling in breast cancer
    Yuan, Shyng-Shiou F.
    Hung, Amos C.
    Hou, Ming-Feng
    CANCER RESEARCH, 2014, 74 (19)
12345