3,4-Disubstituted maleimides: synthesis and biological activity

被引：0
|
作者：
Alexey A. Panov
Alexander Yu. Simonov
Sergey N. Lavrenov
Sergey A. Lakatosh
Alexey S. Trenin
机构：
[1] Gause Institute of New Antibiotics,
来源：
Chemistry of Heterocyclic Compounds | 2018年 / 54卷
关键词：
diarylmaleimides; hybrid antibiotics; indolylmaleimides; antimicrobial activity; protein kinase inhibitors;
D O I：
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学科分类号：
摘要：
This review is devoted to methods for the synthesis of 3,4-disubstituted maleimides – compounds that often show pronounced biological activity. We offer classification of synthetic methods, present comparative analysis of various approaches while describing their advantages and drawbacks. The areas of practical applications are indicated for several 3,4-disubstituted maleimide derivatives in the role of pharmaceutical agents or reactive dyes. The majority of the considered publications are from the last 10 years.
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页码：103 / 113
页数：10
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