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Haploinsufficiency of NR3C1 drives glucocorticoid resistance in adult acute lymphoblastic leukemia cells by down-regulating the mitochondrial apoptosis axis, and is sensitive to Bcl-2 blockage
被引:0
|作者:
Haowen Xiao
Yingying Ding
Yang Gao
Li-Mengmeng Wang
Huafang Wang
Lijuan Ding
Xiaoqing Li
Xiaohong Yu
He Huang
机构:
[1] Zhejiang University School of Medicine,Department of Hematology, Sir Run Run Shaw Hospital
[2] Zhejiang University,Institute of Hematology
[3] The People’s Hospital of Zhongshan City,Department of Hematology
[4] The First Affiliated Hospital,Bone Marrow Transplantation Center
[5] Zhejiang University School of Medicine,undefined
来源:
关键词:
Haploinsufficiency;
NR3C1;
Glucocorticoid resistance;
Acute lymphoblastic leukemia;
Mitochondrial apoptosis axis;
Bcl-2 blockage;
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