Cost Effectiveness of High-Dose Intravenous Esomeprazole for Peptic Ulcer Bleeding

被引:0
|
作者
Alan N. Barkun
Viviane Adam
Joseph J. Y. Sung
Ernst J. Kuipers
Joachim Mössner
Dennis Jensen
Robert Stuart
James Y. Lau
Emma Nauclér
Jan Kilhamn
Helena Granstedt
Bengt Liljas
Tore Lind
机构
[1] McGill University Health Centre,Division of Gastroenterology
[2] Montreal General Hospital,Institute of Digestive Diseases
[3] Chinese University of Hong Kong,Department of Gastroenterology and Hepatology
[4] Erasmus MC University Medical Center,Medizinische Klinik und Poliklinik II
[5] University of Leipzig,David Geffen School of Medicine
[6] UCLA and CURE Digestive Diseases Research Center,undefined
[7] Glasgow Royal Infirmary,undefined
[8] AstraZeneca R&D,undefined
来源
PharmacoEconomics | 2010年 / 28卷
关键词
Proton Pump Inhibitor; Esomeprazole; Peptic Ulcer Bleeding; Spanish Setting; Diem Cost;
D O I
暂无
中图分类号
学科分类号
摘要
Background: Peptic ulcer bleeding (PUB) is a serious and sometimes fatal condition. The outcome of PUB strongly depends on the risk of rebleeding. A recent multinational placebo-controlled clinical trial (ClinicalTrials.gov identifier: NCT00251979) showed that high-dose intravenous (IV) esomeprazole, when administered after successful endoscopic haemostasis in patients with PUB, is effective in preventing rebleeding. From a policy perspective it is important to assess the cost efficacy of this benefit so as to enable clinicians and payers to make an informed decision regarding the management of PUB.
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页码:217 / 230
页数:13
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