Lack of Effect of Omeprazole or of an Aluminium Hydroxide/Magnesium Hydroxide Antacid on the Pharmacokinetics of Lumiracoxib

被引：0
|
作者：
Graham Scott
Christine Vinluan Reynolds
Slavica Milosavljev
Wayne Langholff
Magdy Shenouda
Christiane Rordorf
机构：
[1] Novartis Pharmaceuticals,Department of Exploratory Clinical Development
[2] Novartis Pharmaceuticals,Departments of Exploratory Clinical Development, Bioanalytics, and Biostatistics
[3] MDS Pharma Services,Department of Exploratory Clinical Development
[4] Novartis Pharmaceuticals,undefined
来源：
Clinical Pharmacokinetics | 2004年 / 43卷
关键词：
Omeprazole; Single Oral Dose; Cotinine; Magnesium Hydroxide; Tolfenamic Acid;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Objective: To evaluate the effects of multiple doses of omeprazole and of a single dose of an aluminium hydroxide/magnesium hydroxide (Al/Mg) antacid on the single-dose plasma pharmacokinetics of lumiracoxib.
引用
收藏
页码：341 / 348
页数：7
相关论文
共 50 条
  • [1] Lack of effect of omeprazole or of an aluminium hydroxide/magnesium hydroxide antacid on the pharmacokinetics of lumiracoxib
    Scott, G
    Reynolds, CV
    Milosavljev, S
    Langholff, W
    Shenouda, M
    Rordorf, C
    CLINICAL PHARMACOKINETICS, 2004, 43 (05) : 341 - 348
  • [2] The effect of a combination antacid preparation containing aluminium hydroxide and magnesium hydroxide on rosuvastatin pharmacokinetics
    Martin, Paul D.
    Schneck, Dennis W.
    Dane, Aaron L.
    Warwick, Michael J.
    CURRENT MEDICAL RESEARCH AND OPINION, 2008, 24 (04) : 1231 - 1235
  • [3] Magnesium hydroxide/aluminium hydroxide-containing antacid does not affect the pharmacokinetics of the targeted phosphodiesterase 4 inhibitor roflumilast
    Nassr, Nassr
    Lahu, Gezim
    Huennemeyer, Andreas
    von Richter, Oliver
    Knoerzer, Dietrich
    Reutter, Felix
    Zech, Karl
    Hermann, Robert
    JOURNAL OF CLINICAL PHARMACOLOGY, 2007, 47 (05): : 660 - 666
  • [4] Effects of a magnesium aluminium hydroxide containing antacid, cimetidine or ranitidine on the pharmacokinetics of metrifonate and its metabolite DDVP
    Heinig, R
    Boettcher, M
    Herman-Gnjidic, Z
    Pierce, CH
    CLINICAL DRUG INVESTIGATION, 1999, 17 (01) : 67 - 77
  • [5] Effect of an Antacid (Aluminum Hydroxide/Magnesium Hydroxide/Simethicone) or a Proton Pump Inhibitor (Omeprazole) on the Pharmacokinetics of Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) in Healthy Adult Subjects
    Patel, Gina
    Gupta, Vipul K.
    Gasink, Leanne
    Bajraktari, Floni
    Lei, Yang
    Jain, Akash
    Srivastava, Praveen
    Talley, Angela K.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2023, 67 (04)
  • [6] Calcination effect on magnesium hydroxide and aluminium hydroxide for the development of magnesium aluminate spinel
    Sarkar, R
    Das, SK
    Banerjee, G
    CERAMICS INTERNATIONAL, 2000, 26 (01) : 25 - 28
  • [7] Effects of a Magnesium/Aluminium Hydroxide-Containing Antacid,Cimetidine or Ranitidine on the Pharmacokinetics of Metrifonate and its Metabolite DDVP
    R. Heinig
    M. Boettcher
    Z. Herman-Gnjidic
    C. H. Pierce
    Clinical Drug Investigation, 1999, 17 : 67 - 77
  • [8] Effect of aluminum hydroxide magnesium hydroxide antacid and bismuth subsalicylate on gastric pH in horses
    Clark, CK
    Merritt, AM
    Burrow, JA
    Steible, CK
    JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 1996, 208 (10) : 1687 - &
  • [9] Effect of an Al/Mg Hydroxide Antacid and Food on the Pharmacokinetics of Dexibuprofen
    Shaker, M. Ahsan
    Akhtar, Naveed
    Minhas, Muhammad Usman
    Khan, Kifayat Ullah
    Zangi, Muhammad Imad-ud-Din
    Munir, Abubakar
    DRUG RESEARCH, 2020, 70 (04) : 158 - 164
  • [10] EVALUATION OF ANTACID SUSPENSIONS CONTAINING ALUMINUM HYDROXIDE AND MAGNESIUM-HYDROXIDE
    HEM, SL
    WHITE, JL
    BUEHLER, JD
    LUBER, JR
    GRIM, WM
    LIPKA, EA
    AMERICAN JOURNAL OF HOSPITAL PHARMACY, 1982, 39 (11): : 1925 - 1930
12345