Tolerability and pharmacokinetics of non-fixed and fixed combinations of artesunate and amodiaquine in Malaysian healthy normal volunteers

被引:0
|
作者
Visweswaran Navaratnam
Surash Ramanathan
Mohd Suhaimi Ab. Wahab
Gan Siew Hua
Sharif Mahsufi Mansor
Jean-René Kiechel
Michel Vaillant
Walter R. J. Taylor
Piero Olliaro
机构
[1] Universiti Sains Malaysia (USM),National Center for Drug Research (CRD)
[2] Hospital Universiti Sains Malaysia (HUSM),Pharmacology Laboratory, CTU
[3] Drugs for Neglected Diseases initiative (DNDi),Clinical Trial Unit, School of Medical Sciences, Health Campus
[4] Public Research Centre–Health,Centre for Health Studies
[5] Université Victor Segalen Bordeaux II,Unité 3677, Bases thérapeutiques des inflammations
[6] Hôpitaux Universitaires de Genève,Service de Médicine Internationale et Humanitaire
[7] UNICEF/UNDP/WB/WHO Special Programme for Research & Training in Tropical Diseases (TDR),undefined
关键词
Amodiaquine; Artesunate; Fixed combination treatment; Pharmacokinetics; Non-fixed combination treatment; Tolerability;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:809 / 821
页数:12
相关论文
共 50 条
  • [1] Tolerability and pharmacokinetics of non-fixed and fixed combinations of artesunate and amodiaquine in Malaysian healthy normal volunteers
    Navaratnam, Visweswaran
    Ramanathan, Surash
    Wahab, Mohd Suhaimi Ab.
    Hua, Gan Siew
    Mansor, Sharif Mahsufi
    Kiechel, Jean-Rene
    Vaillant, Michel
    Taylor, Walter R. J.
    Olliaro, Piero
    EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2009, 65 (08) : 809 - 821
  • [2] Comparative oral bioavailability of non-fixed and fixed combinations of artesunate and amodiaquine in healthy Indian male volunteers
    Fortin, Anny
    Verbeeck, Roger K.
    Jansen, Frans H.
    EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2011, 67 (03) : 267 - 275
  • [3] Comparative oral bioavailability of non-fixed and fixed combinations of artesunate and amodiaquine in healthy Indian male volunteers
    Anny Fortin
    Roger K. Verbeeck
    Frans H. Jansen
    European Journal of Clinical Pharmacology, 2011, 67 : 267 - 275
  • [4] Fixed dose artesunate amodiaquine – a phase IIb, randomized comparative trial with non-fixed artesunate amodiaquine
    Bernhards Ogutu
    Elizabeth Juma
    Charles Obonyo
    Vincent Jullien
    Gwenaelle Carn
    Michel Vaillant
    Walter Robert John Taylor
    Jean-René Kiechel
    Malaria Journal, 13
  • [5] Fixed dose artesunate amodiaquine - a phase IIb, randomized comparative trial with non-fixed artesunate amodiaquine
    Ogutu, Bernhards
    Juma, Elizabeth
    Obonyo, Charles
    Jullien, Vincent
    Carn, Gwenaelle
    Vaillant, Michel
    Taylor, Walter Robert John
    Kiechel, Jean-Rene
    MALARIA JOURNAL, 2014, 13
  • [6] Pharmacokinetics and tolerability of artesunate and amodiaquine alone and in combination in healthy volunteers
    Catherine Orrell
    Francesca Little
    Peter Smith
    Peter Folb
    Walter Taylor
    Piero Olliaro
    Karen I. Barnes
    European Journal of Clinical Pharmacology, 2008, 64 : 683 - 690
  • [7] Pharmacokinetics and tolerability of artesunate and amodiaquine alone and in combination in healthy volunteers
    Orrell, Catherine
    Little, Francesca
    Smith, Peter
    Folb, Peter
    Taylor, Walter
    Olliaro, Piero
    Barnes, Karen I.
    EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2008, 64 (07) : 683 - 690
  • [8] SAFETY, EFFICACY AND PHARMACOKINETIC COMPARISON OF FIXED-DOSE ARTESUNATE-AMODIAQUINE "ASAQ" WITH NON-FIXED COMBINATION OF AS AND AQ AMONG KENYAN ADULTS
    Ogutu, Bernhards
    Juma, Elizabeth
    Jullien, Vincent
    Carn, Gwenaelle
    Kiechel, Jean-Rene
    AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2009, 81 (05): : 85 - 85
  • [9] A Replicate Designed Bioequivalence Study To Compare Two Fixed-Dose Combination Products of Artesunate and Amodiaquine in Healthy Chinese Volunteers
    Liu, Yun
    Hu, Chaoying
    Liu, Gangyi
    Jia, Jingying
    Yu, Chen
    Zhu, Jianmin
    Zheng, Qingsi
    Zhang, Kanyin E.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2014, 58 (10) : 6009 - 6015
  • [10] Pharmacokinetics and Ex Vivo Antimalarial Activity of Artesunate-Amodiaquine plus Methylene Blue in Healthy Volunteers
    Chu Xuan Anh
    Chavchich, Marina
    Birrell, Geoffrey W.
    Van Breda, Karin
    Travers, Thomas
    Rowcliffe, Kerryn
    Lord, Anton R.
    Shanks, G. Dennis
    Edstein, Michael D.
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2020, 64 (03)