Dopaminergic modulation of emotional memory in Parkinson’s disease

被引:0
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作者
Thomas D. Hälbig
Ute A. Kopp
Franziska Wodarz
Joan C. Borod
Jean-Michel Gracies
Georg Ebersbach
Andreas Kupsch
机构
[1] Charité,Department of Neurology
[2] Universitätsmedizin Berlin,Department of Neurology
[3] Mount Sinai School of Medicine,Department of Psychology, Queens College and The Graduate Center
[4] City University of New York,Department of Movement Disorders
[5] Neurologisches Fachkrankenhaus,Fédération de Neurologie & Centre d’Investigation Clinique
[6] Centre Hospitalier Universitaire Pitié-Salpêtrière,undefined
来源
关键词
Parkinson’s disease; Emotional memory; Basal ganglia; Dopamine;
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摘要
The aim of this study was to assess the effect of dopaminergic treatment on emotional memory in patients with Parkinson’s disease (PD). We tested memory for emotional and neutral visual stimuli in ten non-demented PD patients on and off dopaminergic medication. Patients recalled significantly more emotional items during the off- than on-medication testing session. In contrast, treatment condition did not affect memory for neutral items. These findings demonstrate that emotional memory deficits observed in PD may result from dopaminergic treatment and suggest an involvement of dopaminergic neurotransmission in emotional processing.
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页码:1159 / 1163
页数:4
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