Membranous nephropathy associated with familial chronic ulcerative colitis in a 12-year-old girl

被引:0
|
作者
Regina M. Ridder
Hans W. Kreth
Eva Kiss
Hermann J. Gröne
Nader Gordjani
机构
[1] University of Würzburg,Children’s Hospital
[2] Deutsches Krebsforschungszentrum,Kinderklinik
[3] Städtisches Klinikum Offenbach,undefined
来源
Pediatric Nephrology | 2005年 / 20卷
关键词
Chronic inflammatory bowel disease; Chronic ulcerative colitis; Vasculitis; Membranous nephropathy;
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学科分类号
摘要
Glomerulonephritis is a rare complication in patients with inflammatory bowel disease. We report a case of membranous nephropathy (MN) in a 12.6-year-old girl with chronic ulcerative colitis. The girl was referred to the hospital with bloody diarrhea and arthralgia. Routine urinalysis showed 1 g/m2 protein excretion in 24 h. Serum ANCA titers were positive. The diagnoses were confirmed by coloscopy and kidney biopsy. The patient’s mother had also suffered from ulcerative colitis in adolescence. Proteinuria normalized under treatment with prednisone (60 mg/m2/day) and azathioprine, which was initiated to treat the colitis. Chronic ulcerative colitis can be associated with glomerulonephritis.
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页码:1349 / 1351
页数:2
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