Is it time to reconsider the administration of thiamine alone or in combination with vitamin C in critically ill patients? A meta-analysis of clinical trial studies

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作者
Nafiseh Shokri-mashhadi
Ali Aliyari
Zahra Hajhashemy
Saeed Saadat
Mohammad Hossein Rouhani
机构
[1] Isfahan University of Medical Sciences,Food Security Research Center and Department of Clinical Nutrition, School of Nutrition and Food Science
[2] Isfahan University of Medical Sciences,Food Security Research Center and Department of Community Nutrition, School of Nutrition and Food Science
[3] Heinrich Heine Universität,Faculty of Mathematics and Natural Sciences, Department of Computer Sciences
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关键词
Intensive care unit; Thiamine; Vitamin C; Low-dose hydrocortisone; Meta-analysis;
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摘要
Thiamine, co-supplementation of thiamine and vitamin C and co-administration of hydrocortisone, vitamin C and thiamine (HVT) had no significant effect on free days of ventilation and ICU length of stay.HVT could decrease and thiamine supplementation could increase mortality rate in ICU.Co-supplementation of thiamine and vitamin C could decrease SOFA score.
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