The role of free prostate-specific antigen in prostate cancer detection

被引：5
|
作者：
Han M. [1 ]
Potter S.R. [1 ]
Partin A.W. [1 ]
机构：
[1] Department of Urology, James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Marburg 1, 600 North Wolfe Street, Baltimore, 21287, MD
来源：
Current Urology Reports | 2000年 / 1卷 / 1期
关键词：
Human Glandular Kallikrein; Prostate Cancer; Prostate Cancer Detection; Prostate Manipulation; Prostate Volume;
D O I：
10.1007/s11934-000-0039-8
中图分类号：
学科分类号：
摘要：
Prostate-specific antigen (PSA) is the most important serum tumor marker for prostate cancer detection. Free PSA is one of the many molecular forms of PSA that have been identified. Percent free PSA improves the specificity (elimination of unnecessary biopsies) for prostate cancer detection in men with nonsuspicious digital prostate examination and total serum PSA ranges between 4 and 10 ng/ mL. Further study is necessary to determine the optimal clinical utility of percent free PSA in men with a total serum PSA level of less than 4 ng/mL. In addition, the level of free PSA may be affected by many factors, including age, prostate volume, prostate manipulation, sample handling, and type of assay used. © 2000, Current Science Inc.
引用
收藏
页码：78 / 82
页数：4
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