Air-Interface Condition Promotes the Formation of Tight Corneal Epithelial Cell Layers for Drug Transport Studies

被引：0

作者：

Joan-En Chang

Sujit K. Basu

Vincent H. L. Lee

机构：

[1] University of Southern California,Department of Pharmaceutical Sciences, Schools of Pharmacy and Medicine

[2] Advanced Inhalation Research/Alkermes,Department of Ophthalmology, Schools of Pharmacy and Medicine

[3] Inc.,undefined

[4] University of Southern California,undefined

来源：

Pharmaceutical Research | 2000年 / 17卷

关键词：

cultured corneal epithelial cells; air-interface; paracellular permeability;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Purpose. To identify the growth conditions that would favor thedevelopment of a functional primary culture of pigmented rabbit cornealepithelial cells on a permeable support comparable to the intact tissuein bioelectric properties.

引用

页码：670 / 676

页数：6

共 39 条

[1] Air-interface condition promotes the formation of tight corneal epithelial cell layers for drug transport studies
Chang, JE
Basu, SK
Lee, VHL
PHARMACEUTICAL RESEARCH, 2000, 17 (06) : 670 - 676
[2] The effect of air-interface condition on the transport of various hydrophilic compounds in primary corneal epithelial cell culture models
Lee, VL
Chang, JE
Gukasyan, H
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 1999, 40 (04) : S89 - S89
[3] Characterization of active ion transport across primary rabbit corneal epithelial cell layers (RCrECL) cultured at an air-interface
Chang-Lin, JE
Kim, KJ
Lee, VHL
EXPERIMENTAL EYE RESEARCH, 2005, 80 (06) : 827 - 836
[4] Dipeptide transport characteristics of rabbit tracheal epithelial cell monolayers cultured at an air-interface
Yamashita, F
Kim, KJ
Lee, VHL
23RD INTERNATIONAL SYMPOSIUM ON CONTROLLED RELEASE OF BIOACTIVE MATERIALS, 1996 PROCEEDINGS, 1996, : 487 - 488
[5] FORMATION OF TIGHT MONOLAYERS OF GUINEA-PIG AIRWAY EPITHELIAL-CELLS CULTURED IN AN AIR-INTERFACE - BIOELECTRIC PROPERTIES
ROBISON, TW
DORIO, RJ
KIM, KJ
BIOTECHNIQUES, 1993, 15 (03) : 468 - 473
[6] Targeted drug delivery to the respiratory tract: Solute permeability of air-interface cultured rabbit tracheal epithelial cell monolayers
Mathias, NR
Kim, KJ
Lee, VHL
JOURNAL OF DRUG TARGETING, 1996, 4 (02) : 79 - 86
[7] Fluid transport by cultured corneal epithelial cell layers
Yang, H
Reinach, PS
Koniarek, JP
Wang, Z
Iserovich, P
Fischbarg, J
BRITISH JOURNAL OF OPHTHALMOLOGY, 2000, 84 (02) : 199 - 204
[8] BIOELECTRIC PROPERTIES OF RABBIT TRACHEAL EPITHELIAL-CELL MONOLAYERS CULTURED IN AN AIR-INTERFACE
MATHIAS, NR
ROBISON, TW
LEE, VHL
KIM, KJ
FASEB JOURNAL, 1993, 7 (03): : A148 - A148
[9] ACTIVE NA+ AND CL- TRANSPORT ACROSS AIR-INTERFACE CULTURED RABBIT TRACHEAL EPITHELIAL-CELL MONOLAYERS
MATHIAS, NR
KIM, KJ
LEE, VHL
FASEB JOURNAL, 1994, 8 (04): : A142 - A142
[10] Dipeptide Uptake and Transport Characteristics in Rabbit Tracheal Epithelial Cell Layers Cultured at an Air Interface
Fumiyoshi Yamashita
Kwang-Jin Kim
Vincent H. L. Lee
Pharmaceutical Research, 1998, 15 : 979 - 983

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