Treatment of Neurogenic Voiding Dysfunction: An Update

被引:2
|
作者
Stansell L.G. [1 ]
Smith A.L. [1 ]
Jaffe W.I. [1 ]
机构
[1] Division of Urology, Perelman Center for Advanced Medicine, University of Pennsylvania, Philadelphia, PA, 19104, 3400 Civic Center Boulevard, 3rd Floor, West Pavilion
关键词
Anticholinergic; Botulinum A toxin; Neurogenic; Neuromodulation; Overactive; Therapy; Urinary bladder;
D O I
10.1007/s11884-010-0077-0
中图分类号
学科分类号
摘要
The neurophysiology of volitional voiding is a poorly understood and constantly evolving field. Some of the most difficult clinical problems in urology arise from structural or neural deviations from this process. These may occur as a result of traumatic injury, congenital defect, or neurological disease. Neurogenic voiding dysfunction is a frequently encountered disorder with multiple etiologies and nonstandardized care. A pervasive complaint in neurogenic voiding dysfunction is detrusor overactivity and resultant urinary incontinence. However, the results of "ideal" initial therapy-catheterization with or without anticholinergics-have been far from satisfactory. This review attempts to go beyond perfunctory measures to explore recent data on anticholinergic therapies, long-term data on botulinum A toxin injections, and applications of neuromodulation. © 2010 Springer Science+Business Media, LLC.
引用
收藏
页码:37 / 44
页数:7
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