The oral bioavailability of pentosan polysulphate sodium in healthy volunteers

被引：0
|
作者：
R. A. Faaij
N. Srivastava
J. M. T. van Griensven
R. C. Schoemaker
C. Kluft
J. Burggraaf
A. F. Cohen
机构：
[1] Centre for Human Drug Research,
[2] Zernikedreef 10,undefined
[3] 2333 CL Leiden,undefined
[4] The Netherlands e-mail: rf@chdr.nl Tel.: +31-71-5246421,undefined
[5] Fax: +31-71-5246499,undefined
[6] Gaubius Laboratory,undefined
[7] TNO-PG,undefined
[8] Leiden,undefined
[9] The Netherlands,undefined
来源：
European Journal of Clinical Pharmacology | 1999年 / 54卷
关键词：
Key words Pentosan polysulphate sodium; Human volunteer study; Oral bioavailability;
D O I：
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中图分类号：
学科分类号：
摘要：
Objective: Pentosan polysulphate sodium (PPS), a heparin-like drug, is supposed to be orally applicable. The objective of the present study was to assess the oral bioavailability of PPS. However, since specific assays for PPS do not exist, this was done by using primary and secondary effect parameters.
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页码：929 / 935
页数：6
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