Exacerbation of substrate toxicity by IPTG in Escherichia coli BL21(DE3) carrying a synthetic metabolic pathway

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作者：
Pavel Dvorak
Lukas Chrast
Pablo I. Nikel
Radek Fedr
Karel Soucek
Miroslava Sedlackova
Radka Chaloupkova
Víctor de Lorenzo
Zbynek Prokop
Jiri Damborsky
机构：
[1] Masaryk University,Loschmidt Laboratories, Department of Experimental Biology and Research Centre for Toxic Compounds in the Environment RECETOX, Faculty of Science
[2] St. Anne’s University Hospital,International Clinical Research Center
[3] Centro Nacional de Biotecnología CNB-CSIC,Systems and Synthetic Biology Program
[4] Academy of Sciences of the Czech Republic,Institute of Biophysics
[5] Masaryk University,Department of Histology and Embryology, Faculty of Medicine
[6] Masaryk University,Department of Experimental Biology, Faculty of Science
来源：
Microbial Cell Factories | / 14卷
关键词：
Metabolic burden; Substrate toxicity; Heterologous metabolic pathway; Isopropyl β-D-1-thiogalactopyranoside; Lactose; 1,2,3-trichloropropane; Metabolic engineering;
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