Rheumatoid synovial fluid interleukin-17-producing CD4 T cells have abundant tumor necrosis factor-alpha co-expression, but little interleukin-22 and interleukin-23R expression

被引:0
|
作者
Leigh D Church
Andrew D Filer
Esther Hidalgo
Katherine A Howlett
Andrew MC Thomas
Stephen Rapecki
Dagmar Scheel-Toellner
Christopher D Buckley
Karim Raza
机构
[1] School of Immunity and Infection,Rheumatology Research Group, MRC Centre for Immune Regulation, Institute for Biomedical Research
[2] College of Medical and Dental Sciences,undefined
[3] University of Birmingham,undefined
[4] Sandwell and West Birmingham Hospitals NHS Trust,undefined
[5] The Royal Orthopaedic Hospital,undefined
[6] UCB,undefined
关键词
Rheumatoid Arthritis; Peripheral Blood Mononuclear Cell; Rheumatoid Arthritis Patient; Synovial Fluid; Th17 Cell;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 17 条
  • [1] Rheumatoid synovial fluid interleukin-17-producing CD4 T cells have abundant tumor necrosis factor-alpha co-expression, but little interleukin-22 and interleukin-23R expression
    Church, Leigh D.
    Filer, Andrew D.
    Hidalgo, Esther
    Howlett, Katherine A.
    Thomas, Andrew M. C.
    Rapecki, Stephen
    Scheel-Toellner, Dagmar
    Buckley, Christopher D.
    Raza, Karim
    ARTHRITIS RESEARCH & THERAPY, 2010, 12 (05)
  • [2] Interleukin-10, interleukin-12, and tumor necrosis factor-alpha differentially influence the proliferation of human CD8(+) and CD4(+) T-cell clones
    vanBergen, CAM
    Smit, WM
    vanSluijters, DA
    Rijnbeek, M
    Willemze, R
    Falkenburg, JHF
    ANNALS OF HEMATOLOGY, 1996, 72 (04) : 245 - 252
  • [3] Enhanced Expression of mRNA for Interleukin 6 and Tumor Necrosis Factor-Alpha In CD34+Cells of the Bone Marrow In Osteoarthritis
    Hirohata, Shunsei
    Yanagida, Tamiko
    Tomita, Tetsuya
    Yoshikawa, Hideki
    ARTHRITIS AND RHEUMATISM, 2011, 63 (10): : S694 - S694
  • [4] CD5 and CD23 expression on B cells in peripheral blood and synovial fluid of rheumatoid arthritis patients:: relationship with interleukin-4, soluble CD23 and tumour necrosis factor alpha levels
    Loza, E
    Tinturé, T
    Sánchez-Ibarrola, A
    RHEUMATOLOGY, 1999, 38 (04) : 325 - 328
  • [5] Elevated Frequency of Synovial Interleukin-21+ CD4+ T Cells Co-Expressing Tumor Necrosis Factor-a in Rheumatoid Arthritis.
    Lebre, Maria C.
    Vieira, Pedro L.
    Aarrass, Saida
    Newsom-Davis, Thomas
    Tak, Paul P.
    Screaton, Gavin R.
    ARTHRITIS AND RHEUMATISM, 2012, 64 (10): : S985 - S986
  • [6] Quercetin, a bioflavonoid, inhibits the induction of interleukin 8 and monocyte chemoattractant protein-1 expression by tumor necrosis factor-alpha in cultured human synovial cells
    Sato, M
    Miyazaki, T
    Kambe, F
    Maeda, K
    Seo, H
    JOURNAL OF RHEUMATOLOGY, 1997, 24 (09) : 1680 - 1684
  • [7] DISCOORDINATE EXPRESSION OF STROMELYSIN, COLLAGENASE, AND TISSUE INHIBITOR OF METALLOPROTEINASES-1 IN RHEUMATOID HUMAN SYNOVIAL FIBROBLASTS - SYNERGISTIC EFFECTS OF INTERLEUKIN-1 AND TUMOR NECROSIS FACTOR-ALPHA ON STROMELYSIN EXPRESSION
    MACNAUL, KL
    CHARTRAIN, N
    LARK, M
    TOCCI, MJ
    HUTCHINSON, NI
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1990, 265 (28) : 17238 - 17245
  • [8] Decreased interleukin-10 production by neonatal monocytes and T cells: Relationship to decreased production and expression of tumor necrosis factor-alpha and its receptors
    Chheda, S
    Palkowetz, KH
    Garofalo, R
    Rassin, DK
    Goldman, AS
    PEDIATRIC RESEARCH, 1996, 40 (03) : 475 - 483
  • [9] Antioxidants inhibit tumor necrosis factor-alpha mediated stimulation of interleukin-8, monocyte chemoattractant protein-1, and collagenase expression in cultured human synovial cells
    Sato, M
    Miyazaki, T
    Nagaya, T
    Murata, Y
    Ida, N
    Maeda, K
    Seo, H
    JOURNAL OF RHEUMATOLOGY, 1996, 23 (03) : 432 - 438
  • [10] SPECIFIC OVEREXPRESSION OF SYNOVIAL INTERLEUKIN-21+CD4+T CELLS CO-EXPRESING TUMOUR NECROSIS FACTOR IN RHEUMATOID ARTHRITIS: ROLE IN JOINT DESTRUCTION?
    Lebre, M. Cristina
    Vieira, Pedro L.
    Aarrass, Saida
    Newsom-Davis, Thomas
    Tak, Paul P.
    Screaton, Gavin R.
    ANNALS OF THE RHEUMATIC DISEASES, 2013, 72 : A19 - A19