Vitamin D in HIV-Infected patients

被引:54
|
作者
Lake J.E. [1 ]
Adams J.S. [2 ]
机构
[1] Center for Clinical AIDS Research and Education, David Geffen School of Medicine at UCLA, Los Angeles, CA 90035, 9911 W. Pico Boulevard
[2] UCLA-Orthopaedic Hospital Research Center, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-7358, 615 Charles E. Young Drive South
关键词
25(OH)2D.HIV.ART.Efavirenz.Tenofovir; Vitamin D.25(OH)D.1;
D O I
10.1007/s11904-011-0082-8
中图分类号
学科分类号
摘要
Observational studies have noted very high rates of low 25(OH)D (vitamin D) levels in both the general andHIV-infected populations. In HIV-infected patients, low 25(OH)D levels are likely a combination of both traditionalrisk factors and HIV-specific and antiretroviral therapy-specific contributors. Because of this unique risk profile,HIV-infected persons may be at greater risk for low 25(OH)D levels and frank deficiency and/or may respond to standardrepletion regimens differently than HIV-uninfected patients.Currently, the optimal repletion and maintenance dosingregimens for HIV-infected patients remain unknown, as dopotential benefits of supplementation thatmay be unique to the HIV-infected population. This paper reviews data published onHIVinfection and vitamin D health in adults over the last year. © Springer Science+Business Media, LLC 2011.
引用
收藏
页码:133 / 141
页数:8
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