Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5

被引：0

作者：

Roland Züst

Luisa Cervantes-Barragan

Matthias Habjan

Reinhard Maier

Benjamin W Neuman

John Ziebuhr

Kristy J Szretter

Susan C Baker

Winfried Barchet

Michael S Diamond

Stuart G Siddell

Burkhard Ludewig

Volker Thiel

机构：

[1] Institute of Immunobiology,Department of Medicine, Department of Molecular Microbiology, and Department of Pathology & Immunology

[2] Kantonal Hospital St. Gallen,Department of Microbiology and Immunology

[3] School of Biological Sciences,Department of Cellular and Molecular Medicine

[4] University of Reading,undefined

[5] Centre for Infection and Immunity,undefined

[6] Queen's University Belfast,undefined

[7] Institute of Medical Virology,undefined

[8] Justus Liebig University Giessen,undefined

[9] Washington University School of Medicine,undefined

[10] Loyola University Stritch School of Medicine,undefined

[11] Institute for Clinical Chemistry and Pharmacology,undefined

[12] University Hospital,undefined

[13] University of Bonn,undefined

[14] School of Medical and Veterinary Sciences,undefined

[15] University of Bristol,undefined

[16] Vetsuisse Faculty,undefined

[17] University of Zürich,undefined

[18] Present address: Singapore Immunology Network,undefined

[19] Agency for Science,undefined

[20] Technology and Research,undefined

[21] Singapore.,undefined

来源：

Nature Immunology | 2011年 / 12卷

关键词：

D O I：

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中图分类号：

学科分类号：

摘要：

The biological role of 2′-O-methylation of host and viral mRNA has remained elusive. Thiel and co-workers show that this modification modulates the induction of type I interferon and sensitivity to interferon.

引用

页码：137 / 143

页数：6

共 4 条

[1] Ribose 2′-O-methylation provides a molecular signature for the distinction of self and non-self mRNA dependent on the RNA sensor Mda5
Zuest, Roland
Cervantes-Barragan, Luisa
Habjan, Matthias
Maier, Reinhard
Neuman, Benjamin W.
Ziebuhr, John
Szretter, Kristy J.
Baker, Susan C.
Barchet, Winfried
Diamond, Michael S.
Siddell, Stuart G.
Ludewig, Burkhard
Thiel, Volker
NATURE IMMUNOLOGY, 2011, 12 (02) : 137 - U46
[2] Kinetic discrimination of self/non-self RNA by the ATPase activity of RIG-I and MDA5
Louber, Jade
Brunel, Joanna
Uchikawa, Emiko
Cusack, Stephen
Gerlier, Denis
BMC BIOLOGY, 2015, 13
[3] Kinetic discrimination of self/non-self RNA by the ATPase activity of RIG-I and MDA5
Jade Louber
Joanna Brunel
Emiko Uchikawa
Stephen Cusack
Denis Gerlier
BMC Biology, 13
[4] MRNA CAP 2′O-METHYLATION PREVENTS IMMUNE RECOGNITION OF SELF-RNA BY RIG-I
Schuberth, Christine
Ludwig, Janos
Herzner, Anna Maria
Zillinger, Thomas
Kerber, Romy
Goldeck, Marion
Coch, Christoph
Hornung, Veit
Drosten, Christian
Barchet, Winfried
Kuemmerer, Beate M.
Hartmann, Gunther
Schlee, Martin
NUCLEIC ACID THERAPEUTICS, 2011, 21 (05) : A25 - A25

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